What have we learned?
The various comments confirm that the term microbiome means different things to different people.
Lita points out that in the early days when HMP was formed, the NIH officially defined the human microbiome as “all of the microorganisms and their genes and genomes whic... Read More
Prokaryotes are by far the most successful superkingdom in terms of both biochemical diversity and the variety of environments conquered. Bacteria can be found living in all kinds of adverse conditions; from high alkaline lakes, to below freezing temperature, to hot volcanic vents which in some ... Read More
Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More
Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.
Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More
Bravo Randy Schekman!
I strongly support your comments on the tyranny of "impact factors" and I will be pleased to join in efforts to prevent the misuse of these ratings.
Impact Factors have become a symbol of terror for scientists in all disciplines and their use in promotion and other ... Read More
Cells, biological circuits, and individual biomolecules organize themselves and interact with the environment. Use of these capabilities in flexible and economically efficient biotechnological production systems is in the focus of the "Molecular Interaction Engineering" (MIE) project. It is the ... Read More
A mechanism that may help explain the severe forms of schistosomiasis, or snail fever, has been discovered by researchers. Schistosomiasis is one of the most prevalent parasitic diseases in the world. The study in mice may also offer targets for intervention and amelioration of the disease. Alth... Read More
Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, re... Read More
Genomes provide clues for treating leukemia, endometrial cancers
As an educator and researcher at a small liberal arts institution, my success is measured (to me) in watching former students from my classroom and laboratory go on to do great things after graduation. Here, I share some great information about (and by) a former student of mine, Franny Gilman, ... Read More
We continue our semi-annual ritual and post this quick tour of our featured blog posts published since June 2013.
Microbial ‘Starstuff’. Associate blogger Gemma Reguera tells us how the remnants of a dying star become transmuted into microbial stuff, including cellular structures... Read More
Scientists have gotten close to pinning down the origin of Middle East Respiratory Syndrome, a dangerous respiratory disease that emerged in Saudi Arabia 17 months ago.
It turns out the MERS virus has been circulating in Arabian camels for more than two decades, scientists report in a study p... Read More
One way to avoid getting sick while traveling is to only eat fruit that you peel yourself, since plants can filter out bacteria and prevent it from traveling throughout their tissues. Well, why not apply this principle to filtering water directly? A team of scientists have done just that, testi... Read More
Natural disasters such as earthquakes can have far-reaching effects beyond the damage caused on the day they occur. The 2010 earthquake in Haiti damaged the already limited sanitation systems leading to areas without adequate toilet and washing facilities; perfect for the spread of infection dis... Read More
Corralling desperados with names like bacillus and paenibacillus will require ingenuity and an arsenal of weapons. These outlaws aren't rustling cattle—they're making milk sour and cheese soft and crumbly.
For more than a century, milk has been heated to kill any bacteria or pathogens that ca... Read More
How handy would it be if, instead of taking your broken circuit board to the Genius Bar (again), you could just prompt it to heal itself? That’s the futuristic possibility researchers have recently inched ever so slightly toward, with the development of hybrid “living materials” made from bacter... Read More
A Connecticut law requiring flu shots for children entering preschool or daycare has reduced flu-related hospitalizations of young children by 12 percent, according to a new study. The jump in flu vaccinations of young children -- to 84 percent in 2012-2013 from about 68 percent in 2009-2010 -- ... Read More
An international team of scientists has identified the precise biochemical key that wakes up the body’s immune cells and sends them into action against invading bacteria and fungi.
The patented work, published in Nature today, provides the starting point to understanding our first line of defen... Read More
Infectious disease specialists at the Johns Hopkins Children’s Center have identified a protein that regulates the body’s immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune sys... Read More
One genome at a time can be exciting, but two even more so. I’m not entirely sure why this is, although it may explain our fascination with sex. And what if more than two entities were involved? What if the intimacy were not just between two individual organisms, but between a greater number of ... Read More