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The sting in dengue's tail

In a new Science study, Duke-NUS Graduate Medical School Singapore (Duke-NUS) scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defences and spread more efficiently. This research is the first of its kind that examined ... Read More

Felinine Plays a Role in the Chasing and Fighting between Cats and Mice

A recent study found that mice may be controlled to be brave in the fight with their biggest enemy cats after smelling a chemical emitted by them and existed in their urine. Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

TWiM #105: Real bugs with legs

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 108 Letters

Nervous in San Diego writes:


Dear Professors of TWiM,
I was recently introduced to TWiM by a neighbor. For the last few weeks I have been listening to the backlog of TWiM podcasts, mainly while walking our dog. Regrettably, our dog is a lousy conversationalist. L... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!


(15.9 MB, 17.4 minutes)


Show notes: 
Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

BacterioFiles 190 - Bacteriophages Bust Biofilm Beacons

This episode: Engineered phages can both kill bacteria and disrupt their communications!


(14.8 MB, 16.2 minutes)


Show notes: 
Journal Paper


Read More

The next anti-tuberculosis drug may already be in your local pharmacy

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid®). Read More

Virus-like particle vaccine protects mice from many flu strains

A vaccine that protects against a wide variety of influenza viruses (a so-called universal flu vaccine) is a critical public health goal given the significant rates of illness and death caused by seasonal influenza and the potentially devastating effects of a pandemic influenza strain. Now, rese... Read More

Hey Yogurt-Maker, Where'd You Get Those Microbes?

This week is Yogurt Week on NPR it seems with a collection of stories about the microbes involved in yogurt manufacturing.

"Yogurt is a truly living food. The bacteria that transform milk into this thick and sour food also provide a sense of mystique.

For Atanas Valev, they carry the tas... Read More

Harmless bacteria may be helpful against meningococcal outbreaks

Nasal drops of harmless bacteria can inhibit a related bug that sometimes causes meningococcal disease, according to new findings published online in Clinical Infectious Diseases. The study--conducted among college students, a group at higher risk for this often serious illness--suggests a new a... Read More

UGA researchers develop breakthrough tools in fight against cryptosporidium

Athens, Ga. - Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium, a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Their discoveries, published in the journal Nature, will ultimately help researchers in... Read More

BacterioFiles 209 - Myxococcus Menace Motivates Megastructures

This episode: Microbial predators in soil cause microbial prey to build fortifications!


(8.8 MB, 9.5 minutes)


Show notes: 
Journal Paper


Read More

TWiV 307: Ebola aetiology

Tara Smith joins the TWiEBOVsters to discuss the Ebola virus outbreak in west Africa, spread of the disease to and within the US, transmission of the virus, and much more.


Hosts: Vincent Racaniello Read More

New vaccines against an old disease: brucellosis

Brucellosis is a worldwide extended infectious disease of livestock (sheep, goats, cattle, cows, pigs, …) and remains one of the most common zoonotic infections, with more tan 500,000 new human cases worldwide every year. Control and eradication of brucellosis requires the use of animal vaccines... Read More

TWiV 296: The real Batman, Linfa Wang

Vincent visits the Australian Animal Health Laboratory in Geelong, Australia and speaks with Linfa about his work on bats and bat viruses.


Hosts: Vincent Racaniello


Guest:  Read More

Diarrhea in cats

Barbara Hinney and her colleagues from the Institute for Parasitology at the University of Veterinary Medicine, Vienna, screened 298 faecal samples taken from cats across Austria for single-cell intestinal parasites, so called enteric protozoa. The samples came from private households, catteries... Read More

TWiP 88: French foreign lesion

Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene.


Hosts:  Read More

TWiP 89: Day TWiPers

Vincent, Dickson, and Daniel reveal last week's case study and introduce a new one concerning a patient who traveled to Belize.


Hosts: Vincent Racaniello,&... Read More

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