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Cells in Senescence State May Help Slow down Aging and Cancer Treatment

BOC Sciences-Senescence means a state where cells stop further development in their function but clean themselves and remove the extra substance. Scientists found that when cells go into this stage, the growth rate of tumor would slow down, which is true of aging. The finding was made on the lev... Read More

Long Distance Travelers Likely Contributing to Antibiotic Resistance's Spread

Washington, DC – August 20, 2015 - Swedish exchange students who studied in India and in central Africa returned from their sojourns with an increased diversity of antibiotic resistance genes in their gut microbiomes. The research is published 10 August in Antimicrobial Agents and Chemotherapy, ... Read More

Synthetic DNA vaccine against MERS induces immunity in animal study

PHILADELPHIA - A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. Read More

Expression of a single gene lets scientists easily grow hepatitis C virus in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective tr... Read More

TWiM #110: Exploring unseen life with unpronounceable words

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 110 Letters

Trudy writes:


I'm sorry, I may have missed something, but the mechanism behind an effective vaccine is still unclear to me, since infection with F. tularensis does not confer protection. How would a vaccine work?


Katy Bosio replies:


In... Read More

MdlM113: Microorganismos Halofilos Extremos y los virus que las infectan con Josefa Anton

Ambientes extremos: salares del mundo, su microbiota y los virus presentes. Estos son los temas a discutirse en el episodio de hoy de La Radio el Mundo de los Microbios. Nuestra invitada la Dra. Josefa (Pepa) Anton, Catedrática Asociada de la Universidad de Alicante compartirá sus estudios so... Read More

What's lurking in your lungs? Surprising findings emerge from U-M microbiome research

ANN ARBOR, Mich. -- With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Read More

Toilet waste provides knowledge about diseases' global transmission routes

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected. Read More

Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes

Link: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002226

Groundbreaking research on the universality and diversity of microorganisms is now challenging the life sciences to upgrade fundamental theories that once seemed untouchable. To fully appreciate the change that... Read More

Following Maternal Transmission, Group B Strep Mutates to Sicken Infants

Washington, DC - August 18, 2015 - Group B streptococcus, a mostly benign inhabitant of healthy adults, is one of the world’s leading causes of neonatal sepsis and meningitis. A team of French investigators has now shown that such cases might occur when the microbe mutates within the infant foll... Read More

Liver damage in hepatitis C patients significantly underestimated, says Henry Ford study

DETROIT - The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the U.S. Centers for Disease Control and Prevention. Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Unlikely Element Turns up in Enzyme; Commercial Renewable Fuels Might Ultimately Result

Washington, DC – August 14, 2015 - Tungsten is exceptionally rare in biological systems. Thus, it came as a huge surprise to Michael Adams, PhD., and his collaborators when they discovered it in what appeared to be a novel enzyme in the hot spring-inhabiting bacterium, Caldicellulosiruptor besci... Read More

Ebola’s Lessons - How the WHO Mishandled the Crisis

In a biological sense, last year’s Ebola epidemic, which struck West Africa, spilled over into the United States and Europe, and has to date led to more than 27,000 infections and more than 11,000 deaths, was a great surprise.

Local health and political leaders did not know of the presence o... Read More

$7 million grant aids efforts to eliminate neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received a $7 million grant from the Bill & Melinda Gates Foundation aimed at eliminating river blindness and elephantiasis, two neglected tropical diseases that annually sicken millions. Read More

Biologist investigates how gene-swapping bacteria evade antibiotics

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More

BacterioFiles 225 - Implanting Internal Invader Immunity

This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!


(14.5 MB, 15.8 minutes)


Show notes: 
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TWiV 350: Viral gene therapy with Katherine High

Host: Vincent Racaniello


Guest: Katherine A. High


Vincent speaks with Katherine High about her... Read More

Toxoplasma parasite's greedy appetite may be its downfall

Toxoplasma gondii is estimated to chronically infect nearly one-third of the world's population, causing the condition Toxoplasmosis. It is most commonly associated with handling cat feaces and is a particular threat to pregnant women and immune-compromised individuals, such as HIV/AIDS patients... Read More
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