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One Dose of Flu Drug Shortens Fever

A single dose of an investigational influenza drug was able to reduce the duration of fever and viral shedding, researchers said here.

In a combined analysis of two randomized placebo-controlled trials, the neuraminidase inhibitor peramivir (Rapivab), given by injection within 48 hours of sym... Read More

Mapping could help stop Ebola's spread

Whether it’s the Black Death of 1350 or the Ebola virus in West Africa, one thing deadly pandemics have in common is that their progress takes a geographical course. But researcher Lars Skog at KTH Royal Institute of Technology is one of those developing geoinformation systems that can help heal... Read More

Genomic and Cellular Complexity from Symbiotic Simplicity

The more that biologists study symbiotic microorganisms and their vast influence on animals, the more nature’s networkism unfolds in a continuum at different biological scales. In this issue, Van Leuven et al. illuminate how a stable and longstanding animal-microbe mutualism increased its interg... Read More

'Immortal' flatworms: Weapon against bacteria

A novel mode of defense against bacteria, such as the causal agent of tuberculosis or Staphylococcus aureus, has been identified in humans by studying a small, aquatic flatworm, the planarian. This discovery highlights the importance of studying alternative model organisms, and opens the way tow... Read More

MDR Infection Risk Rises With Each Hospital Day

Extended stays in hospital appeared to increase the risk of infection with a multidrug-resistant Gram-negative pathogen, researchers said.

In a single-center study, the risk of such infection rose by 1% for every day in hospital, according to Tonya Smith, PharmD, of the University of Utah.

... Read More

An outbreak of enterovirus 68

During the winter of 1962 in California, a new virus was isolated from the oropharynx of 4 children who had been hospitalized with respiratory disease that included pneumonia and bronchiolitis. On the basis of its physical, chemical, and biological properties, the virus was classified as an ente... Read More

Magical Monsoon:rAiNs and Geosmin

A Geosmin Story:
A Musty / Muddy smell - the earthy odour after a heavy spatter of rain is aesthetic to senses.
A poet sitting in such ambiance lets his thoughts to wander randomly and comes out with a sweet piece of write up.
An Artist can do wonders on his canvas flowing with the mood.
Man... Read More

TWiV 302: The sky is falling

The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68.


Hosts: Vincent Racaniello Read More

Of Terms in Biology: Metagenomic Binning

Summer's almost gone. Imagine you're strolling along the shores of a lake enjoying nature's colors during sunset. Sparkle catches your eyes where the lake languidly laps against the shore. You start pondering whether microbes — and if so which ones, and how many different — cause these glistenin... Read More

Cancer Survivor Saved by Measles Virus Raises Funds for Expanded Trial

After battling blood cancer for 10 years, Stacy Erholtz has no signs of the disease, thanks to an experimental treatment that used an engineered version of the measles virus.

Now, a year after finishing her treatment, the 50-year-old mother of three is transitioning from patient to advocate, ... Read More

Progress in the fight against harmful fungi

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. Molecular analysis of the Candida glabrata fungus mutations led to the discovery of 28 new genes that are partly respon... Read More

Researchers Unlock the Genetic Code of Cancer-Causing Liver Fluke Parasite

An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR’s Genome Institute of Singapore (GIS).

GIS’s DNA analysis technique ha... Read More

Malaria parasites sense and react to mosquito presence to increase transmission

Many pathogens are transmitted by insect bites. The abundance of vectors (as the transmitting insects are called) depends on seasonal and other environmental fluctuations. A new article demonstrates that Plasmodium parasites react to mosquitoes biting their hosts, and that the parasite responses... Read More

Scientists Call for Investigation of Mysterious Cloud-like Collections in Cells

About 50 years ago, electron microscopy revealed the presence of tiny blob-like structures that form inside cells, move around and disappear. But scientists still don’t know what they do — even though these shifting cloud-like collections of proteins are believed to be crucial to the life of a c... Read More

Vaginal Microbe Yields Novel Antibiotic

Bacteria living on human bodies contain genes that are likely to code for a vast number of drug-like molecules — including a new antibiotic made by bacteria that live in the vagina, researchers report in this week's issue of Cell.

The drug, lactocillin, hints at the untapped medical potential... Read More

DIY Droplet Lens, finalist, 2014 Eureka Prize for Innovative Use of Technology

The traditional light microscope is bulky and expensive. Dr Tri Phan and Dr Steve Lee from the Garvan Institute of Medical Research and Australian National University used gravity to manufacture high-performance polymer lenses. These can be seamlessly integrated with 3D printing and mini-LEDs to... Read More

Scientists develop ‘electronic nose’ for rapid detection of C-diff infection

A fast-sensitive “electronic-nose” for sniffing the highly infectious bacteria C-diff, that causes diarrhoea, temperature and stomach cramps, has been developed by a team at the University of Leicester.

Using a mass spectrometer, the research team has demonstrated that it is possible to ident... Read More

A new way to diagnose malaria

Using magnetic fields, technique can detect parasite’s waste products in infected blood cells.

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye... Read More

"Immortal" Cells from Henrietta Lacks Lead to Updated Rules on Genomic Data Sharing

Scientists who work on genomics and are funded by the US National Institutes of Health (NIH) must post their data online so that others can build on the information, the agency has said in an update to its guidelines.

The change, which expands the remit of an earlier data-sharing policy, is ... Read More
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