Back in 2008, doctors in Cambodia made a worrisome discovery. They were having a hard time curing some people of malaria.
Even the most powerful drug wasn't clearing out the parasite from patients' blood as quickly as it should. Malaria had evolved resistance to the last medicine we have agai... Read More
Biologists have worked with the Lambda virus as a model system for more than 50 years but they've never had an overarching picture of the molecular machines that allow it to insert or remove DNA from the cells that it infects. Now they can, thanks to an advance that highlights the intriguingly i... Read More
Scientists try to stay a step ahead of HIV in order to combat drug resistance and to develop better treatments. When a person is infected with HIV, there is an initial burst of virus production. This is when integrase inserts the virus DNA into many human cells, including CD4 T-immune cells, bra... Read More
As the deadly outbreak of Ebola in West Africa continues to claim lives, Wellcome Trust director Dr Jeremy Farrar calls for Africans to be given access to experimental Ebola medication. This joint statement with Prof David Heymann, head of the Chatham House Centre on Global Health Security, and ... Read More
From Discover: "Scientists have long known of the important roles played by the microbes on and in our bodies — our microbiomes. These little guys outnumber our own cells 10 to 1, and they help regulate everything from the energy we get out of food to the health of our immune systems. Now, scien... Read More
In 2011, Emmanuel Nnaemeka Nnadi needed help to sequence some drug-resistant fungal pathogens. A PhD student studying microbiology in Nigeria, he did not have the expertise and equipment he needed. So he turned to ResearchGate, a free social-networking site for academics, and fired off a few e-m... Read More
In the first evidence that natural selection favors an individual's infection tolerance, researchers from Princeton University and the University of Edinburgh have found that an animal's ability to endure an internal parasite strongly influences its reproductive success. Reported in the journal ... Read More
According to new research humble, microscopic organisms can create dripstones in caves. This illustrates how biological life can influence the formation of Earth’s geology - and the same may be happening right now on other planets in space.
According to traditional textbooks dripstones are cr... Read More
The end of bacterial flagella that is near the cell is a marvel of mechanical miniaturization — a molecular wheel that turns, just like the axle of a car. The assembly consists of a stator, the part that holds it in place, and a rotor, the part that turns. The rotor is a beautifully complex str... Read More
It came as a surprise to me recently to realize how much is known about the immune responses of plants and, moreover, how much there is to know. There is, I found, detailed molecular information about how our botanical cousins defend themselves against the onslaught of infectious agents. Perhaps... Read More
Humans are increasingly dependent on algae to suck up climate-warming carbon dioxide from the atmosphere and sink it to the bottom of the ocean. Now, by using a combination of satellite imagery and laboratory experiments, researchers have evidence showing that viruses infecting those algae are d... Read More
A cold breeze blew off the Antarctic plain, numbing the noses and ears of scientists standing around a dark hole in the ice. Flecks of ice crackled off a winch as it reeled the last few meters of cable out of the hole. Two workers in sterile suits leaned over to grab the payload — a cylinder the... Read More
Dave Wiechert of Nashville, Illinois, does good business most years cleaning seed for farmers in preparation for planting season. But this year, Wiechert is doing big business after harvest: cleaning fungus off wheat so farmers can sell it.
The "head scab" fungus can produce vomitoxin, a chem... Read More
An experimental vaccine protected 100 percent of animal models against the highly infectious and virulent bacterium, Clostridium difficile, which causes an intestinal disease that kills approximately 30,000 Americans annually. The research is published ahead of print in Infection and Immunity.
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The jury is still out on the effectiveness of meticillin-resistant Staphylococcus aureus (MRSA) superbug control policies in hospitals, according to leading infectious disease experts. In particular, screening and isolating infected patients -- which have long been regarded as the gold standard ... Read More
Native bacteria living inside mosquitoes prevent the insects from passing Wolbachia bacteria -- which can make the mosquitoes resistant to the malaria parasite -- to their offspring, according to a team of researchers.
The team found that Asaia, a type of bacteria that occurs naturally in Ano... Read More
Bacteria are for the most part gregarious organisms, living predominantly in dense communities consisting of multiple strains. In fact, the majority of infectious bacteria occur as multi-layered structures called biofilms, many of which are composed of multiple types of bacteria. As one can imag... Read More
Antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity, according to a new study. Moreover, the research shows t... Read More
Evolution is largely driven by conflict, not collaboration, according to cell evolutionist Harmit Malik at the Fred Hutchinson Cancer Research Center (FHCRC). Mammalian cells are contentious places, he explains, populated by alien and host genomic sequences fighting for dominance. "In the compet... Read More
Enhancing the discoverability of public health and epidemiology research data is a key to ensuring that it gets more widely used. This was the topic of a recent workshop hosted by the London School of Hygiene and Tropical Medicine, where researchers and data experts explored the findings of a re... Read More