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Sandia researchers find clues to superbug evolution

Imagine going to the hospital with one disease and coming home with something much worse, or not coming home at all.

With the emergence and spread of antibiotic-resistance pathogens, healthcare-associated infections have become a serious threat. On any given day about one in 25 hospital patie... Read More

Viral Infection Might Just Be a Phase...Transition

Many double-stranded DNA viruses infect cells by ejecting their genetic information into a host cell. But how does the usually rigid DNA packaged inside a virus' shell flow from the virus to the cell?

In two separate studies, Carnegie Mellon University biophysicist Alex Evilevitch has shown t... Read More

'Deadly diarrhea' rates nearly doubled in 10 years: Study

Infections with the intestinal superbug C. difficile nearly doubled from 2001 to 2010 in US hospitals without noticeable improvement in patient mortality rates or hospital lengths of stay, according to a study of 2.2 million C. difficile infection cases.

Click "source" to read more. Read More

Pneumonia bacterium leaves tiny lesions in the heart

The long-observed association between pneumonia and heart failure now has more physical evidence, thanks to research in the School of Medicine at The University of Texas Health Science Center at San Antonio.

The researchers found proof that Streptococcus pneumoniae, the leading cause of comm... Read More

Yeast Coaxed To Make Morphine

Genetically manipulated yeast can produce morphine, which could help get around the problems with poppy crops, which include climate, disease and war. Karen Hopkin reports.

Yeast. They already participate in producing some of the most popular pain-killing substances around: beer and wine. Now... Read More

New evidence of ancient multicellular life sets evolutionary timeline back 60 million years

A Virginia Tech geobiologist with collaborators from the Chinese Academy of Sciences have found evidence in the fossil record that complex multicellularity appeared in living things about 600 million years ago – nearly 60 million years before skeletal animals appeared during a huge growth spurt ... Read More

In Hopes Of Fixing Faulty Genes, One Scientist Starts With The Basics

Whether they admit it or not, many (if not most) scientists secretly hope to get a call in October informing them they've won a Nobel Prize.

But I've talked to a lot of Nobel laureates, and they are unanimous on one point: None of them pursued a research topic with the intention of winning th... Read More

The Epstein–Barr Virus Wears Chain Mail

The Epstein–Barr virus and its relatives in the herpesvirus family are known for their longevity. They persist in host tissues for years, causing diseases like mononucleosis, Kaposi's sarcoma and herpes, and are notoriously difficult to kill. University of California, Los Angeles, biophysicist Z... Read More

Central Park Features Worldwide Soil Microbes

"If you want to find unique diversity and if you want to find a wide range of different below-ground organisms, you don't have to travel around the world. You can walk across Central Park."

That statement comes from Noah Fierer, an ecology and evolutionary biology professor at the University ... Read More

Bioinspired coating for medical devices repels blood and bacteria

From joint replacements to cardiac implants and dialysis machines, medical devices enhance or save lives on a daily basis. However, any device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient the device is meant to hel... Read More

Influenza A potentiates pneumococcal co-infection: New details emerge

Influenza infection can enhance the ability of the bacterium Streptococcus pneumoniae to cause ear and throat infections, according to research published ahead of print in the journal Infection and Immunity.

In the study, the investigators infected mice with either influenza alone, pneumococc... Read More

Study reveals how deadly MERS virus enters human cells

Cornell researchers have uncovered details of how the deadly Middle East respiratory syndrome coronavirus (MERS-CoV) enters host cells, findings that help explain how it can infect many cell types – a hallmark of viral pathogenicity. The results also offer possible new avenues for treatment.

... Read More

Chromosome Organization the Pseudomonas Way, Part 1

(Re-)Introducing the Pseudomonads. Despite the somewhat murky provenance of their name, pseudomonads are everything but "pseudo-" in terms of their metabolic versatility: they are bacterial omnivores, heterotrophs yet far from picky. Members of the family Pseudomonadaceae (Gammaproteobacteria) a... Read More

Bacterial Hopanoids – The Lipids That Last Forever

The world of lipids does not always gets its due. Their oleaginous charm is not always appreciated, as we said here before. For example, have you heard of hopanoids? They are made by some bacteria and are an unusual kind of polycyclic lipids that resemble steroids, but with an extra ring. Just l... Read More

Bacterial defense policies

High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin.

Click "source" to read more. Read More

CDC Launches Ebola Response Team

In the two days since the second U.S. Ebola patient was diagnosed, the U.S. Centers for Disease Control and Prevention (CDC) has assembled a new team to battle the threat of Ebola. This team has no steady lineup, but it will be deployed anywhere in the country that sees a new case of Ebola, CDC ... Read More

Cells' powerhouses were once energy parasites: Study upends current theories of how mitochondria began

Parasitic bacteria were the first cousins of the mitochondria that power cells in animals and plants -- and first acted as energy parasites in those cells before becoming beneficial, according to a new study.

Click "source" to read more. Read More

Dear Colleague Letter on the Ebola Virus

Dear Colleague,

In light of the recent emergence of the lethal Ebola virus in the US, the National Science Foundation (NSF) is accepting proposals to conduct non-medical, non-clinical care research that can be used immediately to better understand how to model and understand the spread of Ebo... Read More

Immune response turned up, not down, by flu during pregnancy

Pregnant women have an unusually strong immune response to influenza, an unexpected finding that may explain why they get sicker from the flu than other healthy adults, new research from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford has found.

The ... Read More

Staph ‘gangs’ share nutrients during infection: study

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. Like the individual members of a gang who might be relatively harmless alone, they turn deadly when they get together with their “friends.”

The findings, reported Oct. 8 in... Read More
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