An improved gene therapy strategy using modified human stem cells shows promise in animal models as a functional cure for HIV.
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If thinking about the billions of bacteria taking up residence in and on your body gives you the willies, you probably won’t find it comforting that humans are also full of viruses. These maligned microbes are actually intertwined in the very fibers of our being—about 8 percent of our genetic ma... Read More
Quinn Cummings is a writer of three books, Notes From the Underwire, The Year of Learning Dangerously and Pet Sounds.
When a 'personal choice' becomes a health crisis
I glanced at my phone and frowned — why on earth was my daughter’s pediatrician calling me at seven at night?
Without pr... Read More
E. coli usually brings to mind food poisoning and beach closures, but researchers recently discovered a protein in E. coli that inhibits the accumulation of potentially toxic amyloids—a hallmark of diseases such as Parkinson's.
Amyloids are formed by proteins that misfold and group together, ... Read More
The National Institutes of Health has awarded grants totaling $7.9 million in 2014 to 25 research teams who are unraveling the workings of single cells, as part of an effort to spur development of personalized treatments that target disease at the cellular level. The grants are supported by the ... Read More
The deadly pattern of illnesses began to emerge in 2012 at hospitals in Seattle, Pittsburgh, Chicago. In each case, the culprit was a bacteria known as CRE, perhaps the most feared of superbugs, because it resists even "last defense" antibiotics — and kills up to 40% of the people it infects.
... Read More
Developing and bringing to market effective Ebola vaccines requires extreme measures and unprecedented international cooperation, global health experts said on Monday.
In an interim report on a roadmap for vaccines against the current and any future outbreaks of the deadly virus, infectious d... Read More
Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.
Viroids, the smallest known pathogens, ar... Read More
London Colney - The website Pharmaceutical Microbiology has reviewed the top ten microbiology stories and events that have made the news during 2014.
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Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.
Treating surfaces with cold atmospheric pressure plasma (CAPP) may reduce the risk of transmitting norovirus, a contagious virus leading to stomach pain, nausea and diarrhea, according to a new study.
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Imagine a pill that helps people control diabetes with the body’s own insulin.
Cornell researchers have achieved this feat in rats by engineering human lactobacilli, a common gut bacteria, to secrete a protein called Glucagen-like peptide 1 (GLP-1).
A 2003 study led by Atsushi Suzuki of th... Read More
WASHINGTON, DC--January 20, 2015--Researchers have tracked the genetic mutations that have occurred in the Ebola virus during the last four decades. Their findings, published in mBio®, the online open-access journal of the American Society for Microbiology, identified changes in the current West... Read More
Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome. Satellite RNAs do not encod... Read More
These days, the happiest place on Earth isn't so cheerful. In December, a large number of people started coming down with measles after visiting Disneyland in California. So far, about 80 measles cases have been reported in the state, an unusually large number for a virus that has long been unde... Read More
Researchers from UAB have developed a tool for diagnosing bacterial meningitis that uses the same technology as a home pregnancy test.
The test measures the level of certain proteins that are present in the spinal fluid of patients with bacterial meningitis. If the level is high, the test wil... Read More
One of the difficulties faced by teams responding to the current Ebola outbreak in West Africa is identifying individuals and communities residing in remote areas. Existing maps of these regions either do not exist or are inadequate or outdated. This means that basic data like location of houses... Read More
A new class of compounds may be an effective way to fight a virus that leaves children with serious respiratory infections and might be associated with polio-like symptoms.
Researchers used a technique called X-ray crystallography to learn the precise structure of the original strain of enter... Read More
Viruses are incredibly simple, arguably the most simple living organisms on the planet. They have no brains, no metabolism, and they can’t reproduce on their own. Yet they are able to wreak incredible havoc on our bodies and to outwit the scientifically advanced weapons that humans have invente... Read More
With drug-resistant bacteria on the rise, even common infections that were easily controlled for decades -- such as pneumonia or urinary tract infections -- are proving trickier to treat with standard antibiotics.
New drugs are desperately needed, but so are ways to maximize the effective lif... Read More