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Getting Started with MicrobeWorld

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TWiV 424: FLERVergnügen

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.


Hosts:  Read More

A Microbial Death Star

Star Wars – an epic story of war between the forces of good and evil in a galaxy far, far away. The Death Star – the ultimate weapon of destruction. The story is science fiction, but it could be considered an analogy for the constant battle between our immune system and microbial pathogens. Beli... Read More

Peanuts and Probiotics

The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More

Malaria elimination: Vaccines should be tested on larger groups of volunteers

To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational Biology. The researchers from Erasmus MC Rotterdam and Radboud University Medical Center Nijmegen de... Read More

Penn study identifies potent inhibitor of Zika entry into human cells

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania. Publishing in Cell Reports t... Read More

ReSeqTB Data Platform now available to public

The Rapid Drug Susceptibility Testing Consortium (RDST), coordinated by the Critical Path Institute (C-Path) through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform an... Read More

Malaria transmission may increase when more parasites are transferred via mosquito bite

Mosquitos carrying a greater number of malaria-causing parasites may be more likely to cause infection in the people they bite, according to a new study published in PLOS Pathogens.

More than 100 years have passed since scientists first discovered that infectious mosquitos inject malaria-caus... Read More

Advancing Phage Therapy

New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More

TWiM #143: E-scaffolds and receptor transfer

Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.


Hosts: Vincent... Read More

Viral escape hatch could be treatment target for hepatitis E

The technique that the hepatitis E virus — an emerging liver virus historically found in developing countries but now on the rise in Europe — uses to spread could present a weak spot scientists can exploit to treat the disease, according to a new study.

Princeton University-led researchers re... Read More

TWiM 143 Letters

Peter writes:


Greetings TWiM Team


Thinking about the revised estimates for the number of bacterial and human cells in the body from 10:1 to about 1:1, I was wondering what the microbiome cell to self cells ratio is for different species.


I pr... Read More

New dental implant with built-in reservoir reduces risk of infections

A multidisciplinary team of researchers at KU Leuven (University of Leuven, Belgium) has developed a dental implant that gradually releases drugs from a built-in reservoir. This helps prevent and fight infections.

Our mouth contains many micro-organisms, including bacterial and fungal pathoge... Read More

Do the CDC's Suggested New Quarantine Rules Give Them Too Much Power?

When Kaci Hickox, a Doctors Without Borders nurse, returned to New Jersey from working with Ebola patients in West Africa in 2014, she was surprised by her reception. Instead of a quiet return to her home in Maine after four weeks on the front line of Ebola treatment, she was quarantined by the ... Read More

Blood test can predict life or death outcome for patients with Ebola virus disease

Scientists have identified a ‘molecular barcode’ in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection.

A team at the University of Liverpool, in collaboration with Public Health England, Boston University and oth... Read More

How ‘stealth warrior’ bacteria turn a tick’s gut microbes against itself

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick’s defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection in the United States, human granulocytic anapla... Read More

Why hospital antibiotic management strategies do little to curb resistance

A generation ago, two antibiotic strategies known as cycling and mixing were employed to outwit bacteria. Cycling is like antibiotic crop rotation where certain classes of antibiotics are withdrawn for a period of time. Doctors thought this would combat resistance because bacterial pathogens wou... Read More

TWiV 425: All picornaviruses, all the time

The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.


Hosts: Vincent Racaniel... Read More

BacterioFiles 283 - Phages Furnish Photosynthetic Fortifications

This episode: Viruses infecting photosynthetic bacteria could transfer immunity to other viruses between their hosts!


(6.8 MB, 7.4 minutes)


Show notes: 


Read More

Team discovers how bacteria exploit a chink in the body’s armor

Scientists have discovered how a unique bacterial enzyme can blunt the body’s key weapons in its fight against infection.

Researchers at the University of Illinois at Urbana-Champaign and Newcastle University in the U.K. are investigating how infectious microbes can survive attacks by the bod... Read More

Industrial Microbiology Market Expected to Reach US$ 9.4 Bn in 2016, North America Most Profitable Market Globally

The global industrial microbiology market is expected to witness a y-o-y growth of 6.7% in 2016 over 2015 and reach US$ 9.46 Bn in revenues. North America will continue to be the most lucrative market, accounting for over 25% of the market share.

In addition to increase in food consumption, r... Read More
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