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TWiM #133: Right under our noses

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter, an... Read More

The cities of the future could be built by microbes

Today in Phys.org, Martyn Dade-Robertson explores the possibility of using microbes to produce natural cement. This process, called biomineralisation, was discovered deep under water off the coast of the Greek island of Zakynthos.
Future implications for biomineralisation include self-healing ... Read More

Yes, There Are Lots of Germs on the Subway, but Most Are Harmless

Every day, more than 18 million pairs of hands are touching those surfaces in New York’s subway system, the largest in the nation.
bacteria on bus

Boston’s T, the United States' fourth busiest mass transit system, sees 569,200 passengers on any given workday. Since each of those people has a... Read More

Drones transport microbiological samples without altering their content

Robots help sort patient samples, test clinical specimens, and analyze the results. Now a study shows that robots, in the form of drones, can help move our samples from place to place, with little effect on the analytical outcome.

Drone transport made a news splash when Amazon proposed using ... Read More

WSJ: Microbial Nanowires

Researchers as the University of Massachusetts are working with Geobacter by manipulating their genetic material. This manipulation makes the bacteria produce filaments of tryptophan, increasing the electrical conductivity of the bacteria by 2,000 times.

The uses for these nanowires could be... Read More

Nature World News: Antarctic Sea Ice Houses Bacteria Capable of Coverting Mercury to Neurotoxin

Scientists have confirmed that the bacteria Nitrospina is present in Antarctic Sea Ice. Nitrospina has "the genetic ability to convert mercury to a potent neurotoxin known as methylmercury". If ingested, this neurotoxin can cause developmental and physical problems for fetuses, babies, and young... Read More

Science Magazine: New antibiotic found in human nose

With drug-resistant bacteria on the rise, scientists believe the nose is engaging in "microbial warfare". Scientists in Germany have identified that Staphylococcus lugdunensis, found in the nose, excretes a compound they named lugdunin. This compound prevents S. aureus from growing. S. aureus ca... Read More

ASMCUE Happenings 2016

No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More

The Counterintuitive Way That Microbes Survive in Antarctica

A newly discovered microbe is changing the way scientists think about microbes in cold climates. Marinomonas primoryensis was found in Ace Lake, Antarctica, having attached itself to ice via antifreeze proteins. After a few experiments, scientists believe that M. primoryensis attaches to ice b... Read More

Mosquito saliva enhances virus replication and disease

Mosquito saliva, which is injected into the host as a mosquito probes for a blood vessel, contains a collection of chemicals which include anticoagulants to prevent blood clotting, vasodilators to keep blood vessels wide, and anesthetics to prevent us from sensing the mosquito. Saliva also conta... Read More

Mouse microbes may make scientific studies harder to replicate

The microbes that reside in mice are making it difficult to replicate scientific studies. Despite many researchers best efforts to standardize the environment and conditions that their mice live in, replication isn't always possible. While "cagemates" tend to have the same microbes in their gut,... Read More

BacterioFiles 264 - Small Cells Stimulate Satiety

This episode: Proteins from gut bacteria seems to affect hunger and satiety in their (rodent) hosts!


(7.7 MB, 8.3 minutes)


Show notes: 
Ne... Read More

TWiV Special: DA Henderson, smallpox eradicator

Donald “D.A.” Henderson, a physician, educator, and epidemiologist who led the World Health Organization’s campaign to eradicate smallpox, died at 87 years of age on Aug. 19, 2016. Vincent was fortunate to have the opportunity to speak with DA Henderson in 2014 about his career, the smallpox era... Read More

Fungus causing fatal infections in hospitalized patients has unique growth patterns

One of the important tasks of Public Health England’s Mycology Reference Laboratory is to identify any newly emerging fungal pathogens that could become a public health risk. In recent months, the lab had tracked several clusters of Candida auris infections in British hospitals. The multidrug-re... Read More

Improving the quality of dairy products

Bitter tasting yogurt or cheese may not make it to your refrigerator, but it is produced and the result of pesky bacteria. The microbial composition of raw milk impacts the quality, shelf life, and safety of processed milk and other dairy products. Controlling the quality of these products is tr... Read More

TWiV 403: It's not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine.


Hosts:  Read More

Onward toward a Zika vaccine

On Monday, August 1, the US Centers for Disease Control and Prevention recommended that pregnant women not travel to Wynwood, a neighborhood north of downtown Miami, because health officials in Florida had found that mosquitoes there are actively transmitting Zika, a mosquito-borne virus that ca... Read More

MMP #15: A Scientific Roadmap for Antibiotic Discovery

Host: Jeff Fox with special guests, Carolyn Shore and Ruben Tommasi.


Carolyn Shore of Pew Charitable Trusts in Washington, D.C., and Ruben Tommasi of Entasis Therapeutics in Waltham, Massachusetts, talk with Jeff Fox about what’s needed to identify and develop new antimicrobial agents... Read More

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