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New Tools in Fight Against Virus that Attacks the Brain

Researchers have developed new insight into a rare but deadly brain infection, called progressive multifocal leukoencephalopathy (PML). This disease – which is caused by the JC virus – is most frequently found in people with suppressed immune systems and, until now, scientists have had no effect... Read More

Antibacterial Gene Transfer Across the Tree of Life

Though horizontal gene transfer (HGT) is widespread, genes and taxa experience biased rates of transferability. Curiously, independent transmission of homologous DNA to archaea, bacteria, eukaryotes, and viruses is extremely rare and often defies ecological and functional explanations. Here, we ... Read More

A novel plate based method for screening DOPA / melanin producing bacteria

Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More

An Ebola virus protein can cause massive inflammation and leaky blood vessels

Ebola GP protein covers the virus' surface and is shed from infected cells during infection. Shed GP can trigger massive dysregulation of the immune response and affect the permeability of blood vessels.

Click 'source" to read more. Read More

VIBRIO CHOLERAE O1 ISOLATEDFROM HUMAN STOOL

THIS IS VIBRIO CHOLERAE O1 OGAWA ISOLATED FROM HUMAN STOOL SWAB PLATED ON BILE SALT AGAR Read More

Scripps Research Institute Scientists Reveal Weak Spots in Ebola’s Defenses

New Study Exposes How ZMapp Therapy Attacks Virus and Suggests Strategies to Improve It.

Scientists at The Scripps Research Institute (TSRI) have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to se... Read More

UCI team develops test to rapidly diagnose bloodstream infection

New technology can detect bacterial invaders with unprecedented speed, sensitivity.

A new bloodstream infection test created by UC Irvine researchers can speed up diagnosis times with unprecedented accuracy, allowing physicians to treat patients with potentially deadly ailments more promptly... Read More

Delaying ART in Patients with HIV Reduces Likelihood of Restoring CD4 Counts

A larger percentage of patients with human immunodeficiency virus (HIV) achieved normalization of CD4+ T-cell counts when they started antiretroviral therapy (ART) within 12 months of the estimated dates of seroconversion (EDS) rather than later, according to a report published online by JAMA In... Read More

BacterioFiles 193 - Milk Modifies Monkey Microbes

This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!


(7.7 MB, 8.4 minutes)


Show notes: 
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Animals steal defenses from bacteria

It's a dog eat dog world, and bacteria have been living in it for a long time. It's of no surprise that bacteria have a sophisticated arsenal to compete with each other for valuable resources in the environment. In 2010, work led by University of Washington Department of Microbiology Associate P... Read More

Peptic ulcer, cancer bacteria therapy discovery

A common ingredient in vegetable oils may help reduce infection with a bacterium that can cause stomach cancer and peptic ulcers, according to a study by UC San Diego scientists.

The ingredient, linolenic acid, killed the bacterium Helicobacter pylori in mice and reduced inflammation without ... Read More

A POISONOUS CURE

Take two poisonous mushrooms, and call me in the morning. While no doctor would ever write this prescription, toxic fungi may hold the secrets to tackling deadly diseases.

A team of Michigan State University scientists has discovered an enzyme that is the key to the lethal potency of poisonou... Read More

Sophisticated HIV Diagnostics Adapted for Remote Areas

Diagnosing HIV and other infectious diseases presents unique challenges in remote locations that lack electric power, refrigeration, and appropriately trained health care staff. To address these issues, researchers funded by the National Institutes of Health (NIH) have developed a low-cost, elec... Read More

Schistosomas: Tropical parasite uses swim stroke not shared by any other creature

For many bacteria and parasites looking to get a load of the fresh nutritional bounty inside your body, the skin is the first and most important gatekeeper. Schistosomas, however, and burrow right on through. These waterborne blood flukes, responsible for 200 million total worldwide cases of Sch... Read More

New study reveals why some people may be immune to HIV-1

Natural genetic variation in a protective antiviral enzyme holds promise for new therapies.

Doctors have long been mystified as to why HIV-1 rapidly sickens some individuals, while in others the virus has difficulties gaining a foothold. Now, a study of genetic variation in HIV-1 and in the c... Read More

Is HIV Evolving Into A Weaker Virus?

Viruses are masters at mutating.

So the big concern with deadly viruses, like Ebola and hepatitis C, is that they will evolve into more dangerous forms over time.

It looks like just the opposite is happening with HIV — although it's happening slowly.

"HIV can generate any mutation in th... Read More

Resistance and Futility

Scientists reveal how penicillin deals bacteria a devastating blow – work that may lead to new antibiotics.

Penicillin, the wonder drug discovered in 1928, works in ways that are still mysterious almost a century later. One of the oldest and most widely used antibiotics, it attacks enzymes th... Read More

New antimicrobial edible films increase lifespan of cheese

New coatings to apply to soft cheese have been developed by researchers. These coatings are totally edible and have an antimicrobial capacity, which increases the lifespan of the cheese. These films incorporate oregano and rosemary essential oils as antimicrobial agents, and chitosan, a by-produ... Read More

TWiM 93 Letters

David writes:


Why not eat locusts? Assuming you can find any fuel to cook em, and apart from deficiency illnesses, I've always wondered why people didn't hunker down and harvest them for emergency food. Did original peoples endure swarms by eating them? Did Euro food ... Read More

Ebola Free-for-All Could Trigger Bad Science and Wasted Efforts

Everybody and his uncle, it seems, has an idea of something that might work to cure people infected with the deadly virus.

When it comes to treatments for Ebola, there has been a nearly four-decade-long drought. Nothing in the medical arsenal attacks the virus directly. For the most part, p... Read More
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