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Flaviviruses unexpectedly shut off host translation

It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.

In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More

Bacterial communities of the female genital tract impact HIV infection risk

A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More

MdlM119: Las secuencias CRISPR: Su descubrimiento y sus futuras aplicaciones

El sistema CRISPR, su descubrimiento y posibles applicaciones:  En el episodio de hoy contamos con la presencia del Dr. Francisco Mojica de la Universidad de Alicante. 


Aprovechamos una visita suya a la Universidad de Puerto Rico para poder compartir la trayectoria de uno de... Read More

Super “Resolution”: Reflections on Microscopy in the New Year

As we shake off the holidays, 2017 brings a new opportunity for personal reflection. For many trainees, it is also a great time to focus one’s professional goals, including those related to microbiology and microscopy. In celebration of the new year, I’d like to reflect on some of the advanced m... Read More

Infant's prolonged infection reveals mutation that helps bacteria tolerate antibiotics

A life-threatening infection in an infant with leukemia led to a St. Jude Children’s Research Hospital discovery of how prolonged infection sets the stage for bacterial persistence despite antibiotic susceptibility

The quest to understand a prolonged infection in an infant being treated for l... Read More

Bacterial protein structure could aid development of new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don’t. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

Yet one step in the process has remained a mystery because the molecu... Read More

TWiV 423: Dry, well formed, and light brown

The TWiV academia discuss induction of diarrhea by the capsid protein of an astrovirus, and association of a fungal RNA virus with white-nose syndrome of North American bats.


Hosts: Vinc... Read More

NIAID officials call for continued Zika research

Although cases of Zika virus infection appear to be decreasing, the mosquito-borne virus likely will become endemic in the Americas and continue to cause outbreaks and sporadic cases. Given the serious complications of Zika virus infection, particularly in cases of congenital infection, research... Read More

Cholera bacteria infect more effectively with a simple twist of shape

The bacteria that cause the life-threatening disease cholera may initiate infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate the intestines of their unwitting victims, according to a study led by Princeton University.

The researchers discover... Read More

First Full Genome Analysis Solves the Mystery of How Zika Got So Dangerous

The mention of Zika can strike fear in the hearts of pregnant women. With infections increasing around the world, including in the US, researchers are fighting the clock to figure out how the virus can have such horrific effects in some people. Read More

University of Miami Physicians Publish Case Study of First Locally Acquired Zika Infection

Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians with the University of Miami Health System and Miller School of Medicine published a case study January 11 in the New England Journal of Medicine, describing in detail the nation’s first locally trans... Read More

BacterioFiles 281 - Prokaryote Partners Produce Plastic

This episode: Microbes with complementary abilities help each other grow and produce useful stuff from the air!


(12 MB, 13.2 minutes)


Show notes: 


Journal Paper:

Smith MJ, Francis MB. 2016. Read More

TWiV 424: FLERVergnügen

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.


Hosts:  Read More

Genetically engineered mosquitoes resist dengue fever virus

After decades of research and countless control attempts, dengue fever--a mosquito-borne viral disease--continues to infect an estimated 390 million people around the world each year. Now, researchers have reported in PLOS Neglected Tropical Diseases that the mosquitos that carry dengue virus (D... Read More

Peanuts and Probiotics

The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More

Better Diagnosis of Fungal Infections Key to Reducing Antibiotic Resistance

Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases.

“Inadequate attention is paid to fungal infection as the cause of antibacterial t... Read More

Researchers Use Innovating Methods to Study Vertical Transmission of Microbes

It has been assumed that mothers pass on gut microbes to their infants during and just after delivery, a process called vertical transmission, but because of technical restraints, the evidence of this occurring has been limited. Previous cultivation-free studies have observed the same microbial ... Read More

Drug-resistant 'nightmare bacteria' show worrisome ability to diversify and spread

A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely—and more stealthily—than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

Researchers examined carbapenem resi... Read More

Malaria elimination: Vaccines should be tested on larger groups of volunteers

To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational Biology. The researchers from Erasmus MC Rotterdam and Radboud University Medical Center Nijmegen de... Read More

Meet your Microbes (video)

They’re on your tongue, under your armpits, in your guts and on your skin. In fact, any place you can think of there are microbes living on, under, or in between there. In their unimaginably large numbers, these micro-organisms determine our lives – even though we never see them. Micropia, the w... Read More
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