The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.
Food-related microbiology can be one of the most fun - or least fun - ways to interact with microbes. In the ‘most fun’ category, scientists and non-scientists alike can use microbes to create delicious foods from fermentative processes; in the ‘least fun’ category, scientists and non-scientists... Read More
In the second of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on RNA viruses, and what they would be doing if they were not scientists.
Host: Read More
Communication of experimental results via publishing is one of the most important steps of the scientific method; if you don’t share your results, how will knowledge within a field grow? A well-written article contextualizes the author’s data into a broader scientific landscape, which allows rea... Read More
This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!
(7 MB, 7.6 minutes)
How is it that we are we able to devote so little of our personal time and energy to producing or acquiring the healthy, safe food that we consume multiple times every day? A large part of the reason we seldom worry about agricultural output is that most of us benefit enormously from modernized,... Read More
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.
Hosts: Read More
This episode: Spherical cyanobacterium Synechocystis acts like a tiny eyeball in sensing light, allowing cells to move closer to light sources!
(9.7 MB, 10.6 minutes)
Show notes: Read More
Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or l... Read More
Evidence suggests that microbes existed on Earth as far back as 3.7 billion years ago, a billion years after the planet formed. Animal remains, however, don't appear in the fossil record until 600 million years ago during the Ediacaran period, though there are indirect signs that animal life may... Read More
Researchers at the Okinawa Institute of Science and Technology Graduate University in Japan are exploring the possibility of disrupting infections by modifying the flagella of infected bacteria. They are doing this by modifying a protein outside of the bacteria and then re-inserting into the ba... Read More
Dear Vincent, Elio, Michael, and Michelle,
I've just recently finished TWiM number 133 and wanted to comment about the use of the term "secondary metabolite" throughout the episode and often in the primary literature. Michael pointed out that a se... Read More
The world's oceans teem with scientific mystery, unknowns that could prove to be tools that will one day protect the planet from global warming.
An international research team now reports they've tripled the known types of viruses living in waters around the globe and have a better idea what ... Read More
With California in its fifth year of severe drought and many western states experiencing another year of unusually dry conditions, plants are stressed.
Agricultural crops, grasses and garden plants alike can get sick and die when factors such as drought and excess sun force them to work harde... Read More
In my previous posting (Part 1), I reflected on the historical change of the new ASM governance. Here I would like to highlight some key issues that I see facing ASM and its new governance structure. This is not a prescriptive list, but rather a list of goals or, if you prefer, a straw man for ... Read More
A University of British Columbia mathematician may have discovered a key to understanding the constantly changing distribution of microbial species in the world's oceans—classify microorganisms by their biochemical function, rather than by their taxonomy.
Researchers have struggled to underst... Read More
Antimicrobial resistance (AMR) is a chilling reality that my patients and I face every day. As an infectious diseases physician, I see increasing numbers of patients with serious or life-threatening infections, and I am running out of antibiotics to treat them. The emergence of MCR-1 and MCR-2—n... Read More
Tardigrades, or water bears, are pudgy, microscopic animals that look like a cross between a caterpillar and a naked mole rat. These aquatic invertebrates are consummate survivors, capable of withstanding a host of extremes, including near total dehydration and the insults of space.
Now, a pa... Read More
How critical illness alters the microbiome, and the consequences of a sewage spill into an aquatic environment, from the TWiM team.