In biology and genetics, the concept of epistasis is what gives rise to the whole being more (or less) than the sum of its parts. The quantitative effect of a given mutation upon the traits of an organism has the potential to depend strongly upon the gene versions present in other parts of the g... Read More
Researchers at the University of Pennsylvania have developed a new, carbon-based nanoscale platform to electrically detect single DNA molecules.
Using electric fields, the tiny DNA strands are pushed through nanoscale-sized, atomically thin pores in a graphene nanopore platform that ultimatel... Read More
It is widely accepted that the shift in case-fatality rate between waves during the 1918 influenza pandemic was due to a genetic change in the virus. In animal models, the infectious dose of influenza A virus was associated to the severity of disease which lead us to propose a new ... Read More
Buruli ulcer is an infectious disease afflicting thousands of children every year. The difficult-to-cure disease, which is caused by bacteria, occurs in tropical or subtropical climate zones and results in open sores and deformities. For the last two years, the international research consortium ... Read More
Hikers may be locked out of hundreds of caves and 30 000 abandoned
mines in the West and Midwest in a government plan to protect bats
The cave closings may come within the week, said Forest Service
spokeswoman Janelle Smith, and are the latest efforts to combat a
disease... Read More
First, you may be asking yourself – Why viral bioinformatics? Good question! Although it’s true that much in the world of bioinformatics can be applied to all manner of protein and DNA sequences, there are a number of resources that are specific for viruses and there are a number of analyses tha... Read More
This episode: Using cold-loving genes to make vaccines!
(4 MB, 4.5 minutes)
Post questions or comments here, at the link above, or email to email@example.com. Thanks for listening! Read More
One of my big headaches at the moment is a patient — call him Ralph — who appears to be one of the most successful small-time alchemists in all of New York.
He creates gold from dross modern-style, filling his prescriptions every month like clockwork and then selling the unopened bottles for... Read More
A team of scientists, led by Mauro Delogu, virologist from the Veterinary Faculty of the Bologna University and researchers from the Istituto Superiore di Sanità, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia and St. Jude Children's Research Hospital (Memphis, Tennessee) ha... Read More
Electronic surveillance is becoming a critical tool in an infection preventionist's arsenal of tools with which to fight healthcare-acquired infections (HAIs). ICT presents the following case studies to highlight the benefits of using informatics in infection prevention and control efforts.
T... Read More
Human history marches to the beat of what? A big brass band? A choir singing hymns? The lub-dub of the human heart? Sonia Shah’s tour-de-force history of malaria will convince you that the real soundtrack to our collective fate is none of these: it is the syncopated whine-slap, whine-slap of ma... Read More
Biologists have demonstrated a connection between multiple sclerosis (MS)—an autoimmune disorder that affects the brain and spinal cord—and gut bacteria.
Details of the findings appear in the Proceedings of the National Academy of Sciences.
Multiple sclerosis results from the progressive d... Read More
When cells are attacked by bacteria they use all means at their disposal to defend themselves. But cellular defence systems can damage the cells themselves and so need to be kept tightly in check. Recent results help us to understand how this is done and give pointers to new ways of combating di... Read More
Public health officials have been working for months to understand whether the XMRV virus poses a risk to the nation’s blood supply. The concern was sparked by a paper published last year in Science that detected the virus in the blood of 67% of chronic fatigue syndrome patients, compared to ju... Read More
Like a burglar with a universal lock pick, many deadly pathogens use the same protein to gain access to the cells of a potential host, researchers have discovered. The new findings could have implications for blocking infections by agents ranging from wheat rust to malaria.
Pathogenic fungi, ... Read More
In a laboratory where almost all the test tubes look green, the tools of modern biotechnology are being applied to lowly pond scum.
Foreign genes are being spliced into algae and native genes are being tweaked.
Different strains of algae are pitted against one another in survival-of-the-f... Read More
As if rows of serrated teeth and an uncanny ability to smell blood weren't deadly enough, sharks now have a new way to harm unsuspecting swimmers: drug-resistance bacteria.
According to recent research in the Journal of Zoo and Wildlife Medicine, sharks and redfish from shores off of Massachu... Read More
Over the last year, there has been a question on the minds of thousands of people that continues to be for the most part unanswered: Why do disinfectants and hand sanitizers kill only 99.9% of germs and not the full 100%? Or, more succinctly, why is there always 0.1% survival? Read More
Scientists have successfully tracked the progression of influenza virus infections within the lungs of mice. Influenza A virus, the type of flu that causes most seasonal and pandemic outbreaks, has been studied extensively in animal models and tissue cultures. However, the way it moves through t... Read More