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Molecular 'kiss of death' flags pathogens

DURHAM, N.C. -- Many bugs that make us sick -- bacteria, viruses, fungi and parasites -- hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles while leaving the rest of the living cell intact. Read More

Interrupting the transmission cycle: A protein required for dengue virus infection of mosquitoes

There is currently no approved specific treatment or vaccine for dengue fever, and an estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on October 22nd in PLOS Pathogens introduces a candidate target for a tra... Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

Role of breast cell infection in flu transmission between mothers and breast-feeding ferrets

Influenza is known as an infectious respiratory disease, but a study published on October 8th in PLOS Pathogens suggests that infected cells in breast tissues could play a role in virus transmission from mothers to breast-feeding infants and vice versa using a ferret model. Read More

3 ANTIBIOTICS GANG UP TO KILL DEADLY STAPH

As a trio, three antibiotics that aren’t individually effective against a drug-resistant staph infection killed the deadly pathogen in test tubes and mice. Read More

Hibernating bats mount a partial immune response against white nose fungus

White-nose syndrome (WNS), an invasive skin infection caused by the Pseudogymnoascus destructans (Pd) fungus has killed millions of bats since it was first seen in North America in 2007. A analysis of gene expression in hibernating bats infected with the destructive fungus published on October 1... Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

Strategies to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Ha... Read More

VIRUSES FROM NEWBORN GUT ARE NEW TO SCIENCE

Shortly after a baby’s birth, bacteria aren’t the only invaders to colonize the gut. Viruses move in, too, according to new research. Read More

Agar Art 2016 Contest Submit by May 6

We hope you've started plating your dishes! Here are some of the 2016 entries thus far. Show us your creative streaking! For contest entry rules visit: www.microbeworl.org/art. Submissions close May 6, 2016 11:59 P.M.EST.Entries pictured from left to right: Symbol of ASM, A Once in a Lifetime Ki... Read More

Ebola medical team develops guidelines for treating infected children

When the Ebola virus outbreak erupted in West Africa in 2014, children infected with the virus -- particularly those under age 5 -- faced overwhelming challenges. Not only was there a high death rate among young children infected with the disease, they often were isolated from their families, le... Read More

Breast cancer drug beats superbug

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiment... Read More

NIH-sponsored clinical trial of chikungunya vaccine opens

An experimental vaccine to protect against the mosquito-borne illness chikungunya is being tested in a Phase 2 trial sponsored by the National Institutes of Health. Results from an initial trial of the vaccine, which was developed by scientists at the NIH National Institute of Allergy and Infect... Read More

ROVING GENE LETS BACTERIA RESIST ‘LAST’ ANTIBIOTICS

A gene that lets bacteria resist polymyxins—the last line of antibiotic defense we have left—has shown up in widespread bacteria samples from pigs and patients in south China, including strains with epidemic potential. Read More

Social yeast cells prefer to work with close relatives to make our beer, bread and wine

Baker's yeast cells living together in communities help feed each other, but leave incomers from the same species to die from starvation, according to new research from the University of Cambridge. Read More

Pseudomonas aeruginosa with pyoverdine extracellular pigment

This strain of Pseudomonas aeruginosa isolated from wound make a green pigment: pyoverdine. Pyoverdine is a fluorescent siderophores for to acquire iron.
Pyoverdine biosynthesis in Pseudomonas aeruginosa and fluorescent Pseudomonads is a complex process.

Credits: dr. Francesco d'Aleo & Robe... Read More

BOROBODUR Temple

This artwork is made from Escherechia coli in Mac Conkey Agar ( MCA ) and shows the other side of the biggest Buddhist temple in Indonesia and Southeast Asia built by the Syailendra dynasty called “Borobudur”, that included one of the wonders of the world from Indonesia.

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New gene a key to fighting sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis. Read More

Urinary tract infection: How bacteria nestle in

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli. It travels along the urethra to the bladder where it triggers painful... Read More

Tug of war among bacteria

At the University of Cologne, biophysicists in the lab of Professor Berenike Maier were now able to show how differential mechanical forces can lead to cell sorting in biofilms, thereby determining their architecture. In their publication in the journal eLife, the team headed by the biophysicist... Read More
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