Gram stained slide from oil enrichment culture, samples enriched from soil. I would love to know what the HUGE bacilli are - can anyone help? Read More
Another major goal of synthetic biology is to engineer unnatural molecules and compounds into systems and tools that mimic those found in biology. For instance, Joanna Aizenberg and her laboratory have pioneered using self-assembling synthetic nanofibers to generate capture-and-release devices t... Read More
Over the past 30 years, the combined efforts of scientists and clinicians have delivered remarkable successes in HIV therapeutics. Since 1987, the FDA has approved more than 30 antiviral drugs, including 12 HIV protease inhibitors and one integrase inhibitor. These drugs stop ~99% of viral repli... Read More
As the bacteria grow within a biofilm, they organize themselves into reproducible patterns and shapes that can be predicted with mathematical models.
Image: Confocal microscopy of a bacterial biofilm composed of Escherichia coli expressing the fluorescent proteins mCherry and sfGFP. The image w... Read More
The in vivo interaction between a Pseudomonas aeruginosa biofilm, on a silicone implant, and the responding polymorphonuclear leukocytes.
Image: SEM imaging depicts the interaction at day 1 post insertion of the implant in the peritoneal cavity of a mouse. The leukocytes (yellow) are damaged wi... Read More
Trypanosoma brucei, a protozoan parasite, is the causative agent of African sleeping sickness in humans (T. b. gambiense and T. b. rhodesiense) and nagana in cattle (T. b. brucei). These diseases result in much economic hardship and morbidity in Sub-Saharan Africa. The life cycle of these organi... Read More
Trichomonas vaginalis is a protozoan parasite of the urogenital tract in men and women and causes a sexually transmitted disease, trichomoniasis, in about half of infected women. Infections are associated with pelvic inflammatory disease, adverse pregnancy outcomes, infertility, an increased inc... Read More
A macrophage (pale brown) interacts with Borrelia cells (blue), the spirochete bacteria that cause Lyme disease. Although the outer membrane of Borrelia contains a strong antigen, the OspC protein, the bacterium successfully evades the human immune system by hiding out in places less accessible ... Read More