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Outbreak of H7N2 Flu in Cats

Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More

Peanuts and Probiotics

The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More

IDRI contributes to first point-of-care Chagas disease diagnostic for US

With Chagas disease becoming more prevalent in the United States, a diagnostic to quickly and easily detect infection is needed. Today, IDRI (Infectious Disease Research Institute) announces that a fusion antigen it developed and patented is being used as part of a Chagas disease diagnostic test... Read More

NIAID officials call for continued Zika research

Although cases of Zika virus infection appear to be decreasing, the mosquito-borne virus likely will become endemic in the Americas and continue to cause outbreaks and sporadic cases. Given the serious complications of Zika virus infection, particularly in cases of congenital infection, research... Read More

A superbug resistant to every available antibiotic in the U.S. kills Nevada woman

If it sometimes seems like the idea of antibiotic resistance, though unsettling, is more theoretical than real, please read on.

Public health officials from Nevada are reporting on a case of a woman who died in Reno in September from an incurable infection. Testing showed the superbug that ha... Read More

Bacterial communities of the female genital tract impact HIV infection risk

A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More

Bacterial protein structure could aid development of new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don’t. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

Yet one step in the process has remained a mystery because the molecu... Read More

University of Miami Physicians Publish Case Study of First Locally Acquired Zika Infection

Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians with the University of Miami Health System and Miller School of Medicine published a case study January 11 in the New England Journal of Medicine, describing in detail the nation’s first locally trans... Read More

Cholera bacteria infect more effectively with a simple twist of shape

The bacteria that cause the life-threatening disease cholera may initiate infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate the intestines of their unwitting victims, according to a study led by Princeton University.

The researchers discover... Read More

Genetically engineered mosquitoes resist dengue fever virus

After decades of research and countless control attempts, dengue fever--a mosquito-borne viral disease--continues to infect an estimated 390 million people around the world each year. Now, researchers have reported in PLOS Neglected Tropical Diseases that the mosquitos that carry dengue virus (D... Read More

Malaria elimination: Vaccines should be tested on larger groups of volunteers

To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational Biology. The researchers from Erasmus MC Rotterdam and Radboud University Medical Center Nijmegen de... Read More

Malaria transmission may increase when more parasites are transferred via mosquito bite

Mosquitos carrying a greater number of malaria-causing parasites may be more likely to cause infection in the people they bite, according to a new study published in PLOS Pathogens.

More than 100 years have passed since scientists first discovered that infectious mosquitos inject malaria-caus... Read More

TWiM #143: E-scaffolds and receptor transfer

Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.


Hosts: Vincent... Read More

TWiM 143 Letters

Peter writes:


Greetings TWiM Team


Thinking about the revised estimates for the number of bacterial and human cells in the body from 10:1 to about 1:1, I was wondering what the microbiome cell to self cells ratio is for different species.


I pr... Read More

Do the CDC's Suggested New Quarantine Rules Give Them Too Much Power?

When Kaci Hickox, a Doctors Without Borders nurse, returned to New Jersey from working with Ebola patients in West Africa in 2014, she was surprised by her reception. Instead of a quiet return to her home in Maine after four weeks on the front line of Ebola treatment, she was quarantined by the ... Read More

First Full Genome Analysis Solves the Mystery of How Zika Got So Dangerous

The mention of Zika can strike fear in the hearts of pregnant women. With infections increasing around the world, including in the US, researchers are fighting the clock to figure out how the virus can have such horrific effects in some people. Read More

10 Things You Need to Know about mSphereDirect

mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More

Super “Resolution”: Reflections on Microscopy in the New Year

As we shake off the holidays, 2017 brings a new opportunity for personal reflection. For many trainees, it is also a great time to focus one’s professional goals, including those related to microbiology and microscopy. In celebration of the new year, I’d like to reflect on some of the advanced m... Read More

Flaviviruses unexpectedly shut off host translation

It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.

In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More

Yeast Fur?

Candida albicans has the ability to form hyphae. When given space on a YPD agar plate, it can spread to take up that space. This organism was inoculated on the surface in a streak and, after an initial incubation at 30C, was incubated at 25C for three weeks. The appearance of the C. albicans as ... Read More
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