A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More
Bacterial cells have an added layer of protection, called the cell wall, that animal cells don’t. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.
Yet one step in the process has remained a mystery because the molecu... Read More
Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians with the University of Miami Health System and Miller School of Medicine published a case study January 11 in the New England Journal of Medicine, describing in detail the nation’s first locally trans... Read More
The bacteria that cause the life-threatening disease cholera may initiate infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate the intestines of their unwitting victims, according to a study led by Princeton University.
The researchers discover... Read More
After decades of research and countless control attempts, dengue fever--a mosquito-borne viral disease--continues to infect an estimated 390 million people around the world each year. Now, researchers have reported in PLOS Neglected Tropical Diseases that the mosquitos that carry dengue virus (D... Read More
To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational Biology. The researchers from Erasmus MC Rotterdam and Radboud University Medical Center Nijmegen de... Read More
Mosquitos carrying a greater number of malaria-causing parasites may be more likely to cause infection in the people they bite, according to a new study published in PLOS Pathogens.
More than 100 years have passed since scientists first discovered that infectious mosquitos inject malaria-caus... Read More
Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.
Greetings TWiM Team
Thinking about the revised estimates for the number of bacterial and human cells in the body from 10:1 to about 1:1, I was wondering what the microbiome cell to self cells ratio is for different species.
I pr... Read More
When Kaci Hickox, a Doctors Without Borders nurse, returned to New Jersey from working with Ebola patients in West Africa in 2014, she was surprised by her reception. Instead of a quiet return to her home in Maine after four weeks on the front line of Ebola treatment, she was quarantined by the ... Read More
The mention of Zika can strike fear in the hearts of pregnant women. With infections increasing around the world, including in the US, researchers are fighting the clock to figure out how the virus can have such horrific effects in some people. Read More
mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More
As we shake off the holidays, 2017 brings a new opportunity for personal reflection. For many trainees, it is also a great time to focus one’s professional goals, including those related to microbiology and microscopy. In celebration of the new year, I’d like to reflect on some of the advanced m... Read More
It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.
In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More
Candida albicans has the ability to form hyphae. When given space on a YPD agar plate, it can spread to take up that space. This organism was inoculated on the surface in a streak and, after an initial incubation at 30C, was incubated at 25C for three weeks. The appearance of the C. albicans as ... Read More
This episode: Microbes with complementary abilities help each other grow and produce useful stuff from the air!
(12 MB, 13.2 minutes)
Smith MJ, Francis MB. 2016. Read More
"What is the best way to test for Trichomonas vaginalis in a cost effective manner? It's a classic trade-off between money and assay sensitivity." Read More
The TWiV academia discuss induction of diarrhea by the capsid protein of an astrovirus, and association of a fungal RNA virus with white-nose syndrome of North American bats.
Food microbiology is an important issue we cover on this blog, because food safety is vital to prevent foodborne illness. The use of technologies like whole-genome sequencing help identify and pinpoint the source of microbial contaminants, but how do microbes become contaminants in the first pla... Read More
Some microbes can form memories—although, inconveniently for scientists who study the process, they don’t do it very often.
Rockefeller University researchers and their colleagues at the University of California, Berkeley, have found a way to make bacteria encode memories much more frequently... Read More