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Esther Lederberg, Pioneer of Bacterial Genetics

“She did pioneering work in genetics, but it was her husband who won a Nobel price.” So said an obituary in the British newspaper The Guardian regarding Esther Lederberg, a North American microbiologist married to Joshua Lederberg from 1946 to 1966 [8]. Being married to and working along such a... Read More

TWiV 295: A nonslip grippe and Lassa's LAMP

The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry.


Hosts: Vincent Racaniello,&n... Read More

Unfertilized egg Ascaris

Female ascaris release unfertilized eggs which are elongated in shape. Eggs are always bile stained. Children are more susceptible towards ascaris infestation. It is one of the major public health problem in developing countries. Read More

Getting a Knit Bacteriophage From a Former Student!

A former student dropped by my lab this morning, and brought me a gift: a knit bacteriophage! Many times, as educators, we hear what we haven't done well, or could do better. Sometimes, like today, we get a priceless "thank you" from a former student. Read More

Terbinafina with Fluconazole. The combination that inhibiting growth of Candida spp

Any ideas or explication why this combination of antimycotics drugs are inhibiting zone of growth of Candida spp. Econazole make the same round. Sabouraud with chloramphenicol agar was used . Read More

Suspected filariform Strongyloides stercoralis

Larva of Strongyloides was seen after performing wet mount method for the detection of stool samples from the community based study. Read More

TWiM #83: Illuminating tuberculosis and cryptococcosis

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 83 Letters

Matt writes:


Hello TWiM team,

It was great seeing some of you at ASM last week in Boston either in passing between sessions or at the live TWiV episode. I have a few questions about the ASM meeting:
What was something that you all took away from ASM th... Read More

Diseases of Another Kind

The drought that has the entire country in its grip is affecting more than the color of people’s lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer than... Read More

New research from Africa on pharmacomicrobiomics

The Human Microbiome Project (HMP) is a global initiative to identify and characterize the microorganisms present at multiple sites in the human body. An international team of researchers reports on new ways to harness the results of the HMP and discusses how changes in the microbiome might affe... Read More

Herbivore drool defeats fungal defence

A report in Biology Letters shows that the drool of herbivores might help defeat the toxic fungal defences of the plants they graze on.

Grazing or cutting some plants induces a noxious chemical to be produced which deters hungry plant-eaters from revisiting them. The chemicals, called alkaloi... Read More

Bacteria swim with bodies and flagella

Using a new technique to track the swimming motion of a single bacterium, researchers have discovered that the movement of the bacterium’s body — not just thrust from the flagellum — allow movement through fluids. The finding could shed new light on the evolution of cell body shape.

Click "so... Read More

Yellow Light Grows the Best Algae for Biofuels

Aaron Wheeler is the director of an interdisciplinary research group at the University of Toronto in Canada. The group develop lab-on-a-chip techniques for applications in biology, chemistry and medicine.

You recently reported an exciting technique that can screen algae grown under different ... Read More

Microbial to Human Cell Ratio: Just Bragging Rights?

Microbiota buffs repeat it often these days, proudly reminding the public that the microbial cells associated with humans outnumber their host cells by a ratio of ten-to-one. In his letter in the February 2014 Microbe, however, Judah L. Rosner of the National Institutes of Health (NIH) makes a s... Read More

D- Zone Test for phenotypic detection of Inducible clindamycin Resistance

A positive D test indicates that the presence of macrolide-inducible resistance to clindamycin produced by an inducible methylase enzyme that alters the common ribosomal binding site for macrolides, clindamycin and the group B streptogrammins (quinupristin). This cross-resistance, called the ML... Read More

Drug Combo Can Sure Hepatitis C in Patients With HIV

A new combination drug therapy cures chronic hepatitis C in most patients also infected with HIV—and without the side effects of current treatments.

The advance is important, researchers say, because about a third of HIV patients in the United States also have hepatitis C. There are an estima... Read More

Ancient genetic material from caries bacterium obtained for the first time

A UAB research concludes that the Streptococcus mutans, one of the principal bacteria causing dental caries, has increased the changes in its genetic material over time, possibly coinciding with dietary changes linked to the expansion of humanity.

Click "source" to read more. Read More

Land of the bacteria-eaters

For hospital workers an outbreak of harmful bacteria in the wards is a nightmare, but what gives bacteria nightmares?

Perhaps the prospect of being eaten alive by a kind of viral parasite called a bacteriophage (bacteria eater): unlike antibiotics, which some bacteria have evolved a resistanc... Read More

Viral relics show cancer's 'footprint' on our evolution

Cancer has left its 'footprint' on our evolution, according to a study which examined how the relics of ancient viruses are preserved in the genomes of 38 mammal species.

Viral relics are evidence of the ancient battles our genes have fought against infection. Occasionally the retroviruses th... Read More

Study examines therapeutic bacteria’s ability to prevent obesity

A probiotic that prevents obesity could be on the horizon.

Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.

“Of course it’s hard to spec... Read More

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