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HIV particles infecting a human T cell

Scanning electron micrograph of HIV particles infecting a human T cell. Credit: NIAID, NIH Read More

'Gut Feelings' Matter in Dx of Kids' Infections

Physicians should pay attention to their "gut feeling" that something may be seriously wrong when assessing a child with an infectious disease -- even if the clinical appearance is reassuring -- an observational study suggested.

Among 3,369 children whose primary care evaluation did not sugge... Read More

New test shows potential for detecting active cases of Lyme disease

George Mason University researchers can find out if a tick bite means Lyme disease well before the bite victim begins to show symptoms.

"If you are bit by a tick, you can't be sure if you will get Lyme disease ― that is the biggest problem right now," says Alessandra Luchini, research assista... Read More

Super Gonorrhea Bacteria Spur New Treatment Regimen in Europe

Pfizer Inc.’s Zithromax or a generic version of the antibiotic pill should be added to the standard treatment for gonorrhea to fight multidrug-resistant strains of the sexually transmitted bacterium, doctors in Europe said.

New European guidelines for sexually transmitted infections recommend... Read More

How Bacteria Talk to Each Other and Our Cells

Bacteria talk to each other using N-acylhomoserine lactones (AHLs) as quorum sensing (QS) signals. This signaling allows the bacteria to control gene expression of virulence factors and biofilms once a critical density has been achieved. This phenomenon, quorum sensing, is important when an infe... Read More

Nine dead from Legionnaires' disease outbreak in Quebec City

The death toll from the outbreak of legionnaires’ disease increased by one to a total of nine in Quebec City on Wednesday, as public-health authorities sought additional help in their inspection of buildings that are suspected of harbouring the deadly Legionnella bacteria.

Authorities also re... Read More

Rare US Meningitis Outbreak Grows, 5 Dead

Another fatality from a growing outbreak of a rare form of meningitis was reported Thursday, raising the death toll to five people, officials said.

In all, 35 people in six states have been sickened from a steroid that was distributed to 23 states, the Centers for Disease Control and Preventi... Read More

Malaria vaccine gives disappointing results

Interim poor results of RTS,S vaccine trial in African children raise question marks over deployment.

A vast phase III clinical trial in Africa of the malaria vaccine candidate RTS,S/AS01 reported disappointing results this morning. The vaccine failed to show substantial protection in the key... Read More

TWiM #54: Dueling injectors and the microgenderome



Hosts: Vincent Racaniello, Michael Schmidt, and  Read More

Ontario reports first pig-to-human H1N1 case

The first Ontario case of a human contracting the H1N1 variant influenza virus from a pig has been confirmed, the province’s chief medical officer said Tuesday.

“It is a first for us in Ontario,” Dr. Arlene King told the Star.

King said an adult male, who is in critical but stable conditio... Read More

Arabian Coronavirus: Plot Thickens But Virus Lies Low

It now appears that the new coronavirus found on the Arabian Peninsula is more widespread than initially thought, even though only two people are known to have gotten sick from it.

At first it seemed likely that the two known cases of illness from the new cousin-of-SARS virus may have been ex... Read More

Drinking Pig Worms to Fight Crohn's Disease

Eight years ago, Herbert Smith (not his real name) did the unthinkable -- he swallowed thousands of microscopic pig whipworm eggs in a desperate try to quell his advancing Crohn's disease.

"There was nothing to it," said Smith, a 33-year old financial analyst from New York. "It was drinking h... Read More

TWiM 44 Letters

Jeff writes:

Hi All - I am getting to the part of my Micro class where I have students analyze antibiograms and noticed a blog pointing to the attached paper. Forgive me if this topic (antibiogram... Read More

Tough germs swap DNA behind noses

Genetic exchange of antibiotic resistance occurs about 10 million times more effectively in the nose than in the blood of animals, report researchers.

Antibiotic resistance results from bacteria’s uncanny ability to morph and adapt, outwitting pharmaceuticals that are supposed to kill them. B... Read More

Bacteria that work together to cause infection (blog post)

There are lots of things I enjoy about studying bacteria. I love their biochemistry and the secret inner workings of their metabolic pathways. I love that everything they do they manage within the confines of a single cell, and I love that you can go into a bacterial cell fairly easily and just ... Read More

TWiV 198 Letters

Edmilson writes:


Dear Vincent,


Great TWIV 197, it is really nice to learn how science was. Fascinating to see how laborious was to do things that nowadays are only "kitology".


Keep up the great podcast.


Cheers,


Edmilson


... Read More

Cancer drug shocks HIV out of hiding

HIV is an exceptional adversary. It is more diverse than any other virus, and it attacks the very immune cells that are meant to destroy it. If that wasn’t bad enough, it also has a stealth mode. The virus can smuggle its genes into those of long-lived white blood cells, and lie dormant for year... Read More

Gram Stains: A Resource for Retrospective Analysis of Bacterial Pathogens

The Gram stain is commonly used in epidemiologic and clinical studies. It involves smearing a sample onto a slide, staining the material using dyes that bind to bacterial cells, and visually inspecting under a microscope. Many epidemiologic and clinical studies of pregnancy, sexually transmitted... Read More

As pretty as a picture (but a lot more deadly): Killer diseases from anthrax to the Black Death as you've never seen them before

They look like works of modern art but these incredible images actually show some of the world’s deadliest diseases - including the Black Death and anthrax.

Many of the specimens can have devastating affects on the human body and have caused major epidemics.

But the bacteria, invisible to ... Read More

Stroke Drug Kills Bacteria That Cause Ulcers and Tuberculosis

A drug currently being used to treat ischemic strokes may prove to be a significant advance in the treatment of tuberculosis and ulcers. In a new research report appearing online in The FASEB Journal, a compound called ebselen effectively inhibits the thioredoxin reductase system in a wide varie... Read More

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