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Resurrecting ancient microbes to understand evolution

When you hear the word “resurrection”, what’s the first thing that comes to mind? Religious miracles? Zombie viruses? The end of the world?

Whatever your mental association, I’m willing to bet it’s not “an emerging scientific discipline." Well, it just so happens a growing community of microb... Read More

Continuing Discussion on Gain of Function

Should scientific journals publish gain-of-function (GOF) studies, especially those involving pathogens with pandemic potential? While journal editors at the American Society for Microbiology have done so after careful consideration, some scientists expressed concern over that decision. A series... Read More

Mycobacterium smegmatis using transmitted light

Isolated colony of Mycobacterium smegmatis grown on TSA for 96 hrs at 37 degrees C. Margin is lobate with an irregular-rhizoid form. Image taken using transmitted light. Read More

The Science Behind Honey’s Eternal Shelf Life

Modern archeologists, excavating ancient Egyptian tombs, have often found something unexpected amongst the tombs’ artifacts: pots of honey, thousands of years old, and yet still preserved. Through millennia, the archeologists discover, the food remains unspoiled, an unmistakable testament to the... Read More

Tube morphology

Three organisms inoculated in TSB to look at tube morphology. From left to right:
Staphylococcus aureus: flocculent growth/turbid, growth throughout the tube.
Mycobacterium smegmatis: pellicle, growth at the top of the tube. M. smegmatis tends to stick to the tube and grow up the side.
Ba... Read More

New drugs for bad bugs

Washington University in St Louis chemist Timothy Wencewicz says we’ll stay ahead of antibiotic resistance only if we find drugs with new scaffolds, or core chemical structures. One promising candidate, an antibiotic made by a bacterium than infects plants, caught his attention because it contai... Read More

Battling Infection With Microbes

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip. Although there are types of bacteria that can make us sick, Caltech professor of biology and biological engineering Sa... Read More

A WORD on the constraints of influenza virus evolution

Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More

BacterioFiles 184 - Fungus Friends Fabricate Fragrance

This episode: Truffle's microbiome helps produce its attractive aromas!


(12.5 MB, 13.6 minutes)


Show notes: 
Journal Paper


<... Read More

A Bacterial Bioluminescent Valentine's Day

In this short post, I celebrate Valentine's Day with words of light---using bioluminescent bacteria! Read More

2,300 tubes containing SARS virus samples missing in France

A major French biomedical research body, the Pasteur Institute, have launched an investigation into the disappearance of some 2,300 test tubes containing samples of the SARS virus. The loss was discovered during an inventory.

The Pasteur Institute filed a so-called 'complaint against X' on Mo... Read More

Alcaligenes faecalis

Streak plate of Alcaligenes faecalis grown on TSA for 48 hr. Read More

New Research on Antibiotic-Resistant Bacteria, Pressure Ulcers, Severe Alcoholic Hepatitis, and More

Two million people suffer antibiotic-resistant infections yearly, and 23,000 die each year as a result. Most of these infections occur in the community, but deaths usually occur in healthcare settings. Cost estimates vary but may be as high as $20 billion in excess direct healthcare costs.

C... Read More

TWiM 80 Letters

Bob writes:


Dear TWIM hosts,


I enjoyed episode 76, "Genetic biopixels and a pathogenic sweet tooth". I really enjoyed hearing about the course that Dr. Schaechter teaches and in particular the work his students did in developing the biosensor. I would like to ... Read More

New research shows that bacteria survive longer in contact lens cleaning solution than previously thought

Each year in the UK, bacterial infections cause around 6,000 cases of a severe eye condition known as microbial keratitis - an inflammation and ulceration of the cornea that can lead to loss of vision. The use of contact lenses has been identified as a particular risk factor for microbial kerati... Read More

‘SUPER-CLONE’ E. COLI COULD BE WORSE THAN HOSPITAL SUPERBUG

Virulent, drug-resistant forms of E. coli that have recently spread around the world emerged from a single strain of the bacteria, not many different strains, as has been widely believed.

The strain—which causes millions of urinary, kidney and bloodstream infections a year—could have a far gr... Read More

Environment influences ability of bacterium to block malaria transmission

The environment significantly influences whether or not a certain bacterium will block mosquitoes from transmitting malaria, according to researchers at Penn State.

The researchers used a species of malaria parasite that affects rodents, Plasmodium yoelii, and the mosquito, Anopheles stephens... Read More

Happy Holidays!

Large TSA plate: yellowish organism is Staph aureus, red organism is Serratia marcescens. Grown for 24 hrs at 37 degrees C. Read More

Bacterial Nanowires: Not What We Thought They Were

New videos of morphing bacteria reveal that the strange, distinguishing features of so-called “electric bacteria” aren’t quite what they at first appeared to be.

For the past 10 years, scientists have been fascinated by a type of “electric bacteria” that shoots out long tendrils like electric... Read More

TWiV 306: This Week in Ebolavirus

 


The Grand Masters of the TWiV discuss Ebola virus transmission, air travel from West Africa, Ebola virus infectivity on surfaces, the Dallas Ebola virus patient, and Ebola virus in dogs.


Hosts:  Read More

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