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Currently approved drugs found active against bioterror threats in laboratory studies of mice

In the most extensive screen of its kind, Texas Biomed scientists have demonstrated the feasibility of repurposing already-approved drugs for use against highly pathogenic bacteria and viruses. The pathogens included emerging diseases and potential bioterror threats ranging from anthrax to the M... Read More

Chicken pox vaccine effective over long term, Kaiser study finds

Once upon a time, not too terribly long ago, getting the chicken pox was practically a rite of passage for kids.

But now, nearly 20 years after approval of a vaccine for the varicella virus, which causes the itchy illness, chicken pox is a rarity. A new study conducted by researchers at Kaise... Read More

Circumcision alters penis microbiome, could explain HIV protection (press release)

Circumcision drastically alters the microbiome of the penis, changes that could explain why circumcision offers protection against HIV and other viral infections. In a study to be published on April 16 in mBio®, the online open-access journal of the American Society for Microbiology, researchers... Read More

New antimicrobial cable eliminates more than 99% of bacteria, fungus and mold

TPC Wire & Cable Corp. ( www.tpcwire.com) announces the launch of their first antimicrobial cable product called DEFENDER® for the industrial food and beverage market. The DEFENDER antimicrobial cable jacket eliminates greater than 99% of bacteria (e.g. E. Coli, Salmonella) and fungus (e.g. Aspe... Read More

The science-themed art of Deb Sklut

During my visit to Berkeley, CA to record TWiV #228, I met Deb Sklut, an artist who is inspired by the power of science. I recorded a brief conversation with Deb which you can view below. Her work can be found at SqueakySqueegeeArt.etsy.com. Read More

Haiti cholera mutations could lead to more severe disease

The cholera strain that transferred to Haiti in 2010 has multiple toxin gene mutations that may account for the severity of disease and is evolving to be more like an 1800s version of cholera, reports a new Northwestern Medicine study.

The strain, "altered El Tor," which emerged around 2000, ... Read More

Engineered Microvessels Provide a 3-D Test Bed for Human Diseases

Mice and monkeys don't develop diseases in the same way that humans do. Nevertheless, after medical researchers have studied human cells in a Petri dish, they have little choice but to move on to study mice and primates.

University of Washington bioengineers have developed the first structure... Read More

Read any ASM Press eBook Free for a Week!

The American Society for Microbiology is celebrating Read an eBook Week* from April 1st to April 5th, 2013. During this time, they are offering full access to many of their titles and you can read your favorite eBooks for free at the ASM Press eBookstore. (Click "source" above for the link.)

... Read More

Microbes or Not, Parasites All

Parasites pose a problem for the semantically-oriented microbiologist. There is no question that unicellular parasites such as Giardia, Plasmodium, or Toxoplasma are microbes, thus we can appropriate them with impunity. But what about parasitic worms? They are clearly not microscopic* and are ta... Read More

Rapid emergence and antigenic diversification of the norovirus 2012 Sydney variant in Denmark, October to December, 2012

The norovirus (NoV) season in Denmark in late 2012 was characterised by an increase in the number of NoV infections caused mainly by the 2012 Sydney variant, but also by the 2009 New Orleans variant. Analysis of approximately 85% of the capsid gene from 10 Sydney 2012 and 9 New Orleans 2009 isol... Read More

Bird flu mutation study offers vaccine clue

So far there have only been isolated cases of bird flu in humans, and no widespread transmission as the H5N1 virus can’t replicate efficiently in the nose. The new study, using weakened viruses in the lab, supports the conclusions of controversial research published in 2012 which demonstrated th... Read More

Newfound gene may help bacteria survive in extreme environments

In the days following the 2010 Deepwater Horizon oil spill, methane-eating bacteria bloomed in the Gulf of Mexico, feasting on the methane that gushed, along with oil, from the damaged well. The sudden influx of microbes was a scientific curiosity: Prior to the oil spill, scientists had observed... Read More

Secrets of bacterial slime revealed

Newcastle University scientists have revealed the mechanism that causes a slime to form, making bacteria hard to shift and resistant to antibiotics.
When under threat, some bacteria can shield themselves in a slimy protective layer, known as a biofilm. It is made up of communities of bacteria h... Read More

Human Infection With Influenza A(H7N9) in China

On 3 April 2013, the China Health and Family Planning Commission notified WHO of an additional four cases of human infection with influenza A(H7N9). The four patients are from Jiangsu province in eastern China. There is no link between the cases.

The patients include a 45-year-old woman with ... Read More

No sign of human transmission in new bird flu appearance: WHO

The World Health Organization says no evidence has emerged to show that a type of bird flu which has killed two Chinese men can be transmitted between people.

Two men in Shanghai, aged 87 and 27, fell sick in late February. A woman in Anhui province also contracted the virus in early March an... Read More

Symbiotic bacteria program daily rhythms in squid using light and chemicals

Glowing bacteria inside squids use light and chemical signals to control circadian-like rhythms in the animals, according to a study to be published on April 2 in mBio®, the online open-access journal of the American Society for Microbiology. The Hawaiian bobtail squid, Euprymna scolopes, houses... Read More

TWiV 233: We're surrounded



Hosts: Vincent Racaniello, Rich Condit, Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Urgent search for flu source

Researchers suspect H7N9 virus is in bird markets as human cases rise rapidly. Virologists know its name: H7N9. What they don’t yet know is whether this novel avian influenza virus — first reported in humans in China less than two weeks ago — will rapidly fizzle out, become established in animal... Read More

4-year-old bird flu 'carrier' worries China

Doctors say the discovery of a 4-year-old carrier of the H7N9 bird flu virus who shows no symptoms of the potentially lethal virus is a worrying development that could make the spread of the infection more difficult to monitor.

The Beijing Municipal Health Bureau said the boy was detected fro... Read More

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