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A new virus in liver cancer

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers at Inserm, the Paris Public Hospitals (AP-HP), Paris Desc... Read More

Armed malaria protein found to kill cancer cells

A new type of cancer therapy based on seemingly unrelated elements of malaria and cancer is showing promise for development. Kairos Therapeutics, a Vancouver-based biotech company spun-out of The Centre for Drug Research and Development (CDRD), has partnered with VAR2 Pharmaceuticals to advance ... Read More

New Ebola cases in single digits another week, says WHO

DAKAR, Senegal - New Ebola cases were in the single digits another week, the World Health Organization said Wednesday, showing that contact tracing efforts are yielding results.

Read More

Vaginal Microbes Influence Whether Mucus Can Trap HIV Virus

Washington, DC —October 6, 2015— HIV particles are effectively trapped by the cervicovaginal mucus from women who harbor a particular vaginal bacteria species, Lactobacillus crispatus. The findings, published this week in mBio, an online open-access journal of the American Society for Microbiolo... Read More

Sexual transmission of Ebola virus in Liberia confirmed using genomic analysis

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR). Read More

TWiM 122 Letters

Hunter writes:


Greetings TWiM crew!
 
I recently learned of a new game (currently getting ready for Alpha and crowd funding) where players will edit microbes at the genetic level and pit them against microbes created by other players. The game is called... Read More

B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More

Killing Dormant HIV with Cancer Drug

BOC Sciences-Recently Scientists found a new way to kill the hiding and dormant Human Immunodeficiency Virus( HIV) by employing a type of cancer drug, which is proved very effective but still waiting for further trial and approval by the US FDA. Read More

TWiP 107: Parasites leave a bad taste in my gut

The TWiPtastic trio solves the case of the Surfer from Switzerland, and reveal how taste-chemosensory tuft cells in the gut regulate immune responses to parasites.


Hosts: Vincent Racaniello,&n... Read More

High rate of Texas bugs carrying Chagas disease

A deadly parasite that causes Chagas disease is widespread in a common Texas insect, according to a new study by University of Texas at El Paso (UTEP) researchers. The finding suggests that the risk of Texans contracting the disease may be higher than previously thought. Read More

In very ill, probiotics don't prevent 'superbugs' from colonizing intestinal tract

Compared with routine medical care, probiotics administered to critically ill patients in intensive care units showed no benefit in preventing the colonization of drug-resistant microbes in the intestinal tract, according to new research at Washington University School of Medicine in St. Louis. Read More

THESE YEAST CELLS SAY ‘HI’ AND OTHERS RESPOND

Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More

MMP #8: Producing yeast strains for making lager beers with new flavor notes

Host: Jeff Fox with special guest, Stijn Mertens.


Mertens, a graduate student working with Kevin Verstrepen at the University of Leuven in Belgium, talks with Jeff Fox about their efforts to develop new yeast strains for making lager beers—imparting novel flavor and aroma notes withou... Read More

Chip-based technology enables reliable direct detection of Ebola virus

A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecules and can be integrated into a simple, portable instrument for use in field situations where r... Read More

TWiP 102: Nursing eosinophils

The TWiPyzoites solve the case of the Uncommon Parasite, and discuss the role of eosinophils in promoting the growth of Trichinella in skeletal muscle.


Hosts:  Read More

Flu remedies help combat E. coli bacteria

Trillions of bacteria populate the human gut - which makes them more common than any other cells in our body. The composition of this bacterial population is very variable and influenced by our diet. Diseases, but also antibiotic treatments can induce significant shifts in this equilibrium. If e... Read More

Health-care providers a major contributor to problem of antibiotic overuse

SALT LAKE CITY - 10 percent of health care providers write an antibiotic prescription for nearly every patient (95 percent or more) who walks in with a cold, bronchitis or other acute respiratory infection (ARI), according to a new Centers for Disease Control and Prevention-supported study publi... Read More

Genetic differences may help explain inconsistent effectiveness of anti-HIV drug

Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection. Read More

Fungi at root of plant drugs that can help, or harm, sick monarch butterflies

Previously, biologists at Emory University and the University of Michigan discovered that butterflies use plant toxins as a drug to cure their offspring of parasitic infections. Now they've dug a little deeper and found that the fungi associated with the roots of milkweed plants change both the ... Read More

TWiV 377: Chicken with a side of Zika

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

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