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Ebola’s Lessons - How the WHO Mishandled the Crisis

In a biological sense, last year’s Ebola epidemic, which struck West Africa, spilled over into the United States and Europe, and has to date led to more than 27,000 infections and more than 11,000 deaths, was a great surprise.

Local health and political leaders did not know of the presence o... Read More

TWiP 106: Trematode stormtroopers in snail wars

The TWiP triumvirate solves the case of the Missionary in Kenya, and review the finding of a soldier caste in flatworms that parasitize snails.


Hosts: Vincent Racaniello Read More

A case of prion disease acquired from contaminated beef

Spongiform encephalopathies are neurodegenerative diseases caused by misfolding of normal cellular prion proteins. A 2014 case of variant Creutzfeldt-Jacob prion disease in the United States was probably caused by eating beef from animals with bovine spongiform encephalopathy (BSE), or mad cow d... Read More

BacterioFiles 244 - Rabbit Viruses Exploding Cancer

This episode: A conversation with Audiommunity hosts about a rabbit virus that may help treat cancer while preventing the treatment from killing the patient!


(39.2 MB, 42.9 minutes)


Show notes: 
Read More

Humans differ in their personal microbial cloud

Abstract
Dispersal of microbes between humans and the built environment can occur through direct contact with surfaces or through airborne release; the latter mechanism remains poorly understood. Humans emit upwards of 106 biological particles per hour, and have long been known to transmit path... Read More

ASM Live at #ICAAC / ICC - Co-contribution of rotavirus vaccines (RVs) and pneumococcal conjugate vaccines (PCVs) in reduction of pediatric hospital burden

Ron Dagan, Professor of Pediatrics and Infectious Diseases at the Pediatric Infectious Disease Unit, Soroka University Medical Center, Israel will discuss his research that showed how the introduction of both pneumococcal conjugate vaccines (PCVs) and rotavirus vaccines (RVs) led to the rapid an... Read More

TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.


Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More

Toxoplasma parasite's greedy appetite may be its downfall

Toxoplasma gondii is estimated to chronically infect nearly one-third of the world's population, causing the condition Toxoplasmosis. It is most commonly associated with handling cat feaces and is a particular threat to pregnant women and immune-compromised individuals, such as HIV/AIDS patients... Read More

The bacteria-fighting super element that’s making a comeback in hospitals: copper

Ancient Egyptians used copper to sterilize chest wounds and drinking water. Greeks, Romans and Aztecs relied on copper compounds to treat burns, headaches and ear infections. Thousands of years later, the ancient therapeutic is being embraced by some hospitals because of its ability to kill bact... Read More

Rapid testing for TB aims to reduce drug resistance, lower mortality rate

Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to globa... Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

TWiP 103: Scroll down, please

The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.


Hosts:  Read More

Ebola post-crisis: Lessons for improving global health security

WASHINGTON (Sept. 11, 2015) - The O'Neill Institute for National and Global Health Law fall colloquium series continues Wednesday, Sept. 16 with a focus on Ebola. Read More

Wasps do a gain-of-function experiment in caterpillars

Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More

New Virus Identified in Blood Supply

Washington, DC – September 22, 2015 - Scientists have discovered a new virus that can be transmitted through the blood supply. Currently, it is unclear whether the virus is harmful or not, but it is related to hepatitis C virus (HCV) and human pegivirus (HPgV), the latter of which was formerly k... Read More

TWiM 117 Letters

Jessica writes:
I just finished listening to Chewates and Coconuts and was so elated to hear about the open access paper comparing the Soybean Oil, Beef Tallow, and Coconut Oil effects on fungal colonization. I am a biologist by education, but I also have quite the “Crun... Read More

BacterioFiles 249 - Spores Survive Spaceship Scorching

This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!


(10.7 MB, 11.25 minutes)


Show notes: 
J... Read More

Sugar governs how antibodies work in the immune system

The immune system is our biological defense shield. Antibodies protect the organism against invading pathogens such as viruses or bacteria. In the case of certain autoimmune diseases, however, this defense behavior is misdirected: The antibodies don't just target foreign substances; they also at... Read More

A new virus in liver cancer

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers at Inserm, the Paris Public Hospitals (AP-HP), Paris Desc... Read More

Armed malaria protein found to kill cancer cells

A new type of cancer therapy based on seemingly unrelated elements of malaria and cancer is showing promise for development. Kairos Therapeutics, a Vancouver-based biotech company spun-out of The Centre for Drug Research and Development (CDRD), has partnered with VAR2 Pharmaceuticals to advance ... Read More
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