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Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


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Gene therapy: 'Heart-healing virus' trial starts

Patients in the UK have been enrolled into a trial to see if an engineered virus can be used to heal their damaged and struggling hearts. The trial will use a virus to introduce genetic material into heart muscle to reverse the organ's decline. The British Heart Foundation said the idea had "gre... Read More

Laser technology shaves time off bacteria turnaround

Scientists at a local laboratory say a new piece of technology there can identify bacteria a day earlier than traditional methods.

"If it's a blood infection or meningitis, getting that identification as fast as we can can mean the difference between life and death," said Karen Calvert, a mic... Read More

Could Adaptable Bacteria Cause Repeat UTIs?

Women suffering from recurring urinary tract infections may carry a particularly hearty strain of E. coli bacteria that flourishes in both the gut and the bladder, and can migrate back and forth despite repeated treatments, a small new study finds.

Doctors believe that urinary tract infection... Read More

The Merlot Microbiome

Plants associated bacteria play a key role in host productivity and health. These bacteria are phylogenetically diverse and form interactions considered neutral, beneficial or detrimental. A better understanding of these interactions will have a direct impact in agriculture by promoting sustaina... Read More

Map of H7N9 fatalities and confirmed infections in China

Shanghai Daily has a web page set up that shows the geographic distribution of H7N9 infections and fatalities in China. There is also a news feed, information on symptoms and a photo gallery. Click "source" to view. Read More

The Art of Microbial Alchemy

In 2001, Kashefi and collaborators published an article in Applied and Environmental Microbiology reporting the surprising finding that several iron-reducing microbes can use gold as an electron acceptor for their respiration. These microbial alchemists included both mesophilic and thermophilic ... Read More

Pandemic Swine Flu Virus Found in Seals

The swine flu virus that caused a 2009 pandemic has been found in elephant seals off the central California coast, according to new research. The study, published in the journal PLoS ONE, is the first report of the virus H1N1 in any marine mammal. Researchers are now being advised to wear protec... Read More

Study defines level of dengue virus needed for transmission

Researchers have identified the dose of dengue virus in human blood that is required to infect mosquitoes when they bite. Mosquitoes are essential for transmitting the virus between people, so the findings have important implications for understanding how to slow the spread of the disease.

By... Read More

Electron Beam Zaps Oysters to Kill Bacteria

Raw oysters, a delicacy for foodies and a purported hangover cure (it isn’t) aren’t always the safest thing to eat. Pathogens such as Vibrio vulnificus, norovirus and Hepatitis A sometimes lurk in oyster flesh. These little nasties can cause food poisoning and norovirus specifically has no treat... Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Algae capture, store, and release nitrogen to feed reef-building coral

Symbiotic algae that live within reef-forming corals scoop up available nitrogen, store the excess in the form or uric acid crystals, and slowly feed it to the coral as needed, according to a study in mBio this week. Scientists have known for years that these symbiotic microorganisms serve up ni... Read More

Lofted by hurricanes, bacteria live the high life

With cold temperatures, low humidity and high levels of ultraviolet (UV) radiation, conditions 10 kilometers above Earth’s surface may seem inhospitable. But next time you’re flying, consider this: The air outside your airplane window might be filled with an array of microscopic life that affect... Read More

Fecal Transplants in the “Good Old Days”

I had a conversation with some colleagues last week about “personalized medicine,” which has been transformed now into the term “precision medicine.” The conversation revolved around what to do about the perceived effects of antibiotic treatment on the microbiota of individuals. How does one tre... Read More

A Good Defense Is Worth Stealing

One widely-used tactic for defense against phage and other mobile genetic elements is to deploy a CRISPR-Cas system (click here and here) to recognize and chop them into pieces. Based on sequenced genomes, 60% of Bacteria and 90% of Archaea have the wherewithal to dispatch invaders this way. But... Read More

Anti-Depressant Link to Clostridium Difficile Infection

Certain types of anti-depressants have been linked to an increase in the risk of Clostridium difficile infection (CDI) finds a study in BioMed Central's open access journal BMC Medicine. Awareness of this link should improve identification and early treatment of CDI.

Certain types of anti-dep... Read More

TWiV 232: Gophers go viral



Hosts: Vincent Racaniello, Roberto Cattaneo, ... Read More

Intestinal Bacteria Protect Against E. Coli O157:H7

A cocktail of non-pathogenic bacteria naturally occurring in the digestive tract of healthy humans can protect against a potentially lethal E. coli infection in animal models according to research presented today at the 113th General Meeting of the American Society for Microbiology. The researc... Read More

UD-led team develops mathematical model to measure hidden HIV

Scientists have long believed that measuring the amount of HIV in a person’s blood is an indicator of whether the virus is actively reproducing.

A University of Delaware-led research team reports new evidence that hidden virus replication may be occurring within the body’s tissue, despite un... Read More

Engineered Microbes Glow In the Dark

Scientists at the University of California, Davis have engineered a strain of photosynthetic cyanobacteria to grow without the need for light. They report their findings today at the 113th General Meeting of the American Society for Microbiology.

“In this work, we used synthetic biology appr... Read More
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