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Chromosome Organization the Pseudomonas Way, Part 1

(Re-)Introducing the Pseudomonads. Despite the somewhat murky provenance of their name, pseudomonads are everything but "pseudo-" in terms of their metabolic versatility: they are bacterial omnivores, heterotrophs yet far from picky. Members of the family Pseudomonadaceae (Gammaproteobacteria) a... Read More

Major step forward in understanding of viruses as scientists unlock exact structure of Hep A virus

Scientists have announced that for the first time, they have determined the precise atomic structure of the Hepatitis A virus. In an unprecedented step forward, a team of scientists from Beijing and Oxford have been able to map the exact construction of Hepatitis A, down to the individual atoms.... Read More

Lessons from the ‘Spanish Flu,’ Nearly 100 Years Later

Just in time for flu season, a new Michigan State University study of “the mother of all pandemics” could offer insight into infection control measures for the flu and other epidemic diseases.

Siddharth Chandra, director of MSU’s Asian Studies Center and professor in MSU’s James Madison Colle... Read More

DNA design in my hand

DNA made in my hand... :) Read More

Mineralization of sand particles boosts microbial water filtration

Mineral coatings on sand particles actually encourage microbial activity in the rapid sand filters that are used to treat groundwater for drinking, according to a paper published ahead of print in Applied and Environmental Microbiology. These findings resoundingly refute, for the first time, the... Read More

Imaging electric charge propagating along microbial nanowires

Physicists report that they've used a new imaging technique, electrostatic force microscopy, to resolve the biological debate with evidence from physics, showing that electric charges do indeed propagate along microbial nanowires just as they do in carbon nanotubes, a highly conductive human-mad... Read More

Fine Reading: Trans-kingdom Cross Talk – Small RNAs on the Move

We have lived with the discovery of small RNAs as regulatory molecules for nearly 30 years, so for most readers of this blog this is old hat. But some of us oldsters are still reeling from the novelty and importance of the findings. It seems odd that a subject of this significance, one that has ... Read More

Evolution of extreme parasites explained by scientists

Extreme adaptations of species often cause such significant changes that their evolutionary history is difficult to reconstruct. Zoologists have now discovered a new parasite species that represents the missing link between fungi and an extreme group of parasites. Researchers are now able to und... Read More

Could Reston virus be a vaccine for Ebola virus?

I have received many questions about whether immunizing with Reston virus could protect against infection with Ebola virus. Usually the question comes together with the statement ‘because Reston virus does not cause disease in humans’. I can think of two reasons why a Reston virus vaccine is not... Read More

Airborne Environmental Isolate/Fungal view 2

Different view of an unknown airborne environmental isolate on Bile Esculin Agar (BEA) exhibiting a single circular colony. White hyphal growth with no spore formation. Clear to brownish exudate can be seen throughout the colony. This sample grew at refrigerated temperatures for several months.... Read More

Positive clinical results indicate vaccine candidate is highly efficacious against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. This repr... Read More

Tick protein does the trick to fight infection

A protein in ticks that protects them against the cold could inspire a new class of antibiotics for humans, according to a Yale University study.

Scientists discovered that IAFGP, an antifreeze protein in ticks that kicks in during winter, also fights infection. Synthesizing such a protein ma... Read More

Chromosome Organization the Pseudomonas Way, Part 2

Studying chromosome organization in bacteria. Over the last twenty years, molecular biologists developed and refined a downright cute method to study bacterial chromosome organization in live cells. Briefly, a cluster of binding sites for a DNA-binding protein is introduced at a chosen locus of ... Read More

Antibiotic Susceptibility Test (AST) Disc in Blood sample

I am sunil pandey from kathmandu Nepal, studying B.Sc in medical microbiology at nobel college. this is AST disc in MHA from blood sample, shows the clear zone of inhibition(Kirby -Bauer disc diffusion Method). I have done this experiment as part of my study "susceptibility of antibiotics in ba... Read More

Viral-research moratorium called too broad

Us government ban on research into enhanced pathogens also affects flu surveillance and vaccine work.

US researchers are worried that a temporary government ban on 'gain-of-function' experiments that boost the infectious properties of dangerous viruses may also cover less-extreme forms of the... Read More

Mycobacterium tuberculosis Bacteria

3D print of Mycobacterium tuberculosis, the bacterium that causes tuberculosis. For more information, visit the NIH 3D Print Exchange at 3dprint.nih.gov.

Credit: National Institutes of Health (NIH) Read More

Amphibian communities collapse in wake of viral outbreak

Two closely related viruses that have been introduced to northern Spain in recent years have already led to the collapse of three different species of amphibian -- the common midwife toad, the common toad, and the alpine newt -- in the protected area of Picos de Europa National Park. In all, six... Read More

Programmable Antibiotics Could Kill Infections While Leaving Your "Good" Bugs Alone

As the world experiences a wakeup call about the rise of drug-resistant infections, a new approach to creating smarter, “programmable” drugs could combat the two major problems with life-saving drugs today.

On the one hand, today’s antibiotics work a little too well. They not only kill infect... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

Complex Life Owes Its Existence To Parasites?

Is complex life rare in the cosmos? The idea that it could be rests on the observation that the existence of life like us – with large, energy hungry, complicated cells – may be contingent on a number of very specific and unlikely factors in the history of the Earth. Added together they suggest ... Read More
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