Genomic analysis of transplant patients finds an opportunistic microorganism whose elevated presence could be used an indicator in treatment.
More than 260,000 Americans are alive today thanks to transplant operations that have replaced their failing kidneys, hearts, lungs or livers with hea... Read More
Scientists at Emory Vaccine Center have found a link between immunity induced by vaccination and an ancient way that cells adapt to scarcity, a link that could help researchers develop vaccines against challenging infections such as HIV or malaria.
Researchers studying immune responses to the... Read More
Natural selection favours those with a greater capacity to generate genetic variation.
Some gamblers succeed by spiriting cards up their sleeves, giving them a wider range of hands to play. So do some bacteria, whose great capacity for genetic variability helps them evolve and adapt to rapidl... Read More
We live in a world run by microbes, the vast majority of which we have yet to identify or name. We can only refer to them collectively as the microbial dark matter (MDM). However you define a prokaryotic species, and however you tally them once identified, there is a huge gap between the 12,000 ... Read More
One would assume offhand that the pathways for synthesis and assembly of the major constituents of a bacterial cell “talk to each other,” i. e. they are tightly interwoven processes. Tampering with the biosynthesis of one should affect all the others, right? Wouldn’t you expect, for instance, th... Read More
The mosquito-borne infection is cropping up in Florida, but mysteriously not in similar regions in the nation.
Most Americans lose little sleep over dengue fever. The mosquito-borne infection is a leading killer in the tropics and subtropics, but it’s been a long-held belief that ubiquitous a... Read More
Food transit through the small intestine affects the body's absorption of nutrients and, consequently, our health. The discovery that food transit time is regulated by a hormone indicates new ways to increase the intestinal absorption of nutrients, and thus potentially treat malnutrition.
One... Read More
Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with “big gun” antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt stud... Read More
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins.... Read More
Saudi Arabia says one more person has died from a new respiratory virus related to SARS, bringing to 55 the number of deaths in the kingdom at the center of the outbreak.
The Health Ministry said Sunday that the 37-year-old man died in Riyadh. He was among 130 people who have been infected wi... Read More
In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More
Cambridge scientists have uncovered the mechanism by which bacteria build their surface propellers (flagella) – the long extensions that allow them to swim towards food and away from danger. The results, published this week in the journal Nature, demonstrate how the mechanism is powered by the s... Read More
Two studies published in the December issue of Infection Control and Hospital Epidemiology show antibiotic resistance patterns for children have held stable over a seven-year period and surgical patients in U.S. children's hospitals account for 43 percent of all antibiotic use in children's hosp... Read More
Evolution is relentless process that seems to keep going and going, even when creatures live in a stable, unchanging world.
That's the latest surprise from a unique experiment that's been underway for more than a quarter-century.
Evolution is so important for biology, medicine and a genera... Read More
There is no approved medicine to treat polyomaviruses, which afflict people with weakened immune systems, but scientists have found that a chemical compound called Retro-2 is able to reduce significantly the infectivity and spread of the viruses in lab cell cultures. Now they are working to impr... Read More
As the year closes out, we enter into the giving seasons of a variety of traditions. Lurking among the more pleasant types of giving is the 2013 – 2014 flu season, a viral gift that often keeps on giving. To combat this, reminders about the potential dangers of influenza and the importance of va... Read More
Slothful response from regulators and manufacturers means antibiotic resistance is missed. Bacteria that are resistant to almost all antibiotics are dreaded by physicians and patients alike. Finding such microbes in a hospital is bad enough, but failing to detect them can lead to something much ... Read More
Looks like Harvard University scientists have given us another reason to walk past the cheese platter at holiday parties and reach for the carrot sticks instead: Your gut bacteria will thank you.
Switching to a diet packed with meat and cheese — and very few carbohydrates — alters the trillio... Read More
The Lyme disease spirochete, Borrelia burgdorferi, is an obligate parasite that cycles between ticks and vertebrate hosts. B. burgdorferi alters the proteins expressed on its outer surface, depending on the state of each host. Here, we used immunofluorescent antibodies to identify spirochetes th... Read More
A common soil-dwelling microbe appears to have a sense of touch, researchers report.
A new study finds that Bacillus mycoides, a bacterium known to science since 1842, responds to forces and curvature in the medium on which it’s growing.
The microbe’s ability to respond to subtle changes i... Read More