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Largest HIV transmission study conducted

A new study has found that neither gay men nor heterosexual people with HIV transmit the virus to their partner, provided they are on suppressive antiretroviral treatment.



The PARTNER study, which is the world's largest study of people with HIV who have had condomless sex with their HIV ... Read More

BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!


(11.1 MB, 12.1 minutes)


Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.


Hosts: Read More

Vibrio cholerae population structure changes in a matter of weeks

Although the Gram-negative bacterium Vibrio cholerae (right) is normally associated with human pathogenic disease, most V. cholerae cells spend their lives in an aquatic environment, and only a few of the many serotypes are able to cause disease. When strains acquire the right genetic makeup – s... Read More

3rd Global Microbiologists Annual Meeting

The organization feels proud and honoured in inviting the contributors across the globe to its premier "3rd Global Microbiologists Annual Meeting" to be held during August 15-17, 2016 at Portland, Oregon, USA.

This year's meeting will showcase the role of microbes in different ecosystems by r... Read More

Dispatches from ASM Microbe: Entire series

Things have been quiet on mBiosphere lately. We've been busy updating from ASM Microbe, covering some of the fascinating research presented there. The first Microbe meeting, which combines the former general meeting and ICAAC, was a whirlwind of poster presentations, lectures, seminars, book sig... Read More

BacterioFiles 257 - Phage Fibers Fight Phyllosphere Foes

This episode: Bacteria have repeatedly captured and used the tails of phages to fight each other!


(9 MB, 9.8 minutes)


Show notes: 
Journal Paper:

Hockett KL, Renner T, Baltrus DA. 2015. Read More

Microbes After Hours: Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathoge... Read More

BacterioFiles 259 - Fluke Froth Fosters Fester Fixing

This episode: I converse with Dr. Michael Smout about a liver fluke parasite could help heal chronic wounds more quickly!


(13.4 MB, 14.6 minutes)


Show notes: 
Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More

TWiV 396: Influenza viruses with Peter Palese

Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.


Host: Vincent Racaniello 


Guest:&nbs... Read More

UMMS scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant professor in microbiology & physiological systems, reveals new lea... Read More

Antibiotic stewardship - a community effort

As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More

Thermos device quickly detects Zika for only $2

Engineers have developed a rapid, low-cost genetic test for Zika. The $2 device, about the size of a soda can, doesn’t require electricity or technical expertise and only needs a bit of saliva. Read More

Diversity and Activity of Communities Inhabiting Plastic Debris in the North Pacific Gyre

Marine plastic debris is a growing concern that has captured the general public’s attention. While the negative impacts of plastic debris on oceanic macrobiota, including mammals and birds, are well documented, little is known about its influence on smaller marine residents, including microbes t... Read More

What does the structure reveal about a colony collapse disorder-associated virus

Colony collapse disorder (CCD) has caused such a profound drop in honeybee populations that even the U.S. Congress is addressing the issue: Senator Jeff Merkley (D-Oregon) has proposed the Pollinator Recovery Act to preserve pollinator habitat. The rapid decline in these important pollinators af... Read More

TWiP 112: A NOD to a tricky helminth

The TWiP trio solve the case of the Woman from Washington Heights, and reveal how helminth infection protects mice deficient in the Crohn's disease gene NOD2 from intestinal disease by inhibiting colonization with an inflammatory bacterial species.


Hosts:  Read More

MMP #14: A look at several microorganisms involved with electricity.

Host: Jeff Fox with special guests, Gemma Reguera and Geoffrey Gadd.


Gemma Reguera of Michigan State University in East Lansing and Geoffrey Gadd of the University of Dundee in Scotland talk with Jeff Fox about their efforts, to probe some of the electrical properties of materials pro... Read More

Environmental disturbances decrease the variability of microbial populations

A central pursuit of microbial ecology is to accurately model changes in microbial community composition in response to environmental factors. This goal requires a thorough understanding of the drivers of variability in microbial populations. However, most microbial ecology studies focus on the ... Read More

TWiV 395: The cancer thief

From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers. 


Hosts:  Read More

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