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A Day in the Life: Eavesdropping on Marine Picoplankton

Observing microbes in nature is a challenge. Compared to what goes on in the lab, there is not much one can do with them out there. So, instead of bringing the bacteria to the lab, why not bring the lab to the bacteria? Imagine being able to capture the expression of genes of a community of micr... Read More

Sequencing tracks animal-to-human transmission of bacterial pathogens

Researchers have used whole genome sequencing to reveal if drug-resistant bacteria are transmitted from animals to humans in two disease outbreaks that occurred on different farms in Denmark. The results, which are published today in EMBO Molecular Medicine, confirm animal-to-human transmission ... Read More

Episode 3: The First Viral Video, Ever!!!!

This is the first Viral Video ever recorded! It was made in 1885 and features Louis Pasteur describing the first rabies vaccine clinical trial. This clearly makes it a viral video and not a bacterial or fungal video!

Enjoy!

(Yes, the first patient was a boy, but things get lost in translat... Read More

Bacteria With Vuvuzelas: Microbes Use a Channel Protein as a Syringe for Toxins

The bacterium Photorhabdus luminescens is a constant companion of some roundworms. These worms assault insect larvae, thereby infecting them with the bacteria; the pathogens then attack the cells of their victims with a deadly cocktail of various toxins. Scientists at the Max Planck Institute of... Read More

The Threat of Emerging and Re-emerging Infectious Diseases to Wildlife

(from National Geographic) In this 6th interview with renowned wildlife biologist Dr. Michael Hutchins, we discuss the challenges facing vanishing species and other threatened free-ranging and captive populations of wildlife due to emerging and re-emerging infectious diseases.

Jordan: Zoonose... Read More

TWiV 225: Transcripts from the inbox



Hosts: Vincent Racaniello, Alan Dove, and Read More

BacterioFiles Micro Edition 118 - Fungi Found in Seafloor Sediments

This episode: Fungi are found living deep under the sea!




Download Episode (3.15 MB, 3.5 minutes)


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Chemical Compounds That Halt Virus Replication Identified

Researchers at Boston University School of Medicine (BUSM) have identified a new chemical class of compounds that have the potential to block genetically diverse viruses from replicating. The findings, published in Chemistry & Biology, could allow for the development of broad-spectrum antiviral ... Read More

Hospitals gain new weapons against deadly bacteria

As the invisible bugs in hospitals get scarier and more prevalent, hospitals are finding new ways to clean.

Doylestown Hospital on Tuesday unveiled its newest high-tech weapon, a machine that zaps everything in a room with ultraviolet light 25,000 times brighter than the sun's. It can penetra... Read More

“10” Predictions for the Future of Your (Microbial) Health

Every day it seems like some new discovery is revealed ab0ut the microbial life on our bodies, in our bodies and around our homes. The tendency in writing about such studies is to make sweeping conclusions about what is and is not and, of course, how we should live and what we should do. But the... Read More

A breakthrough antibiotic? SUNY ESF scientists create synthetic protein that disrupts bacteria growth

When things don't go as planned in Chris Nomura's science world, they sometimes turn out for the better.

Nomura, an assistant professor in the SUNY College of Environmental Science and Forestry's Department of Chemistry, and his team of researchers are using a synthetic protein molecule to di... Read More

Certain Bacteria Suppress Production of Toxic Shock Toxin: Probiotic Potential Looms

Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists from the University of Western Ontario have discovered certain strains of lactobacillus bacteria are capable ... Read More

Chitinase: A Swiss Army tool for environmental pathogens

Humans don't make chitin. So why do many bacterial pathogens require chitinases to maintain an infection? A study in mBio this week reveals that in Listeria monocytogenes, at least, chitinase helps the environmental pathogen live a double life, digesting chitin while the bacterium lives in the s... Read More

Scientists Reveal Quirky Feature of Lyme Disease Bacteria

Unlike most organisms, they don't need iron, but they crave manganese. Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substi... Read More

Bacterial byproduct offers route to avoiding antibiotic resistance

As public health officials sound the alarm about the global spread of drug-resistant bacteria, researchers are working to develop more effective antibiotics to counter this dangerous trend. Now, results from a team including a Princeton University scientist offer a possible solution that uses th... Read More

Biodiversity doesn’t lower disease risk for people

A new analysis pokes holes in a widely accepted theory that connects biodiversity abundance with a reduced disease risk for people. More than three quarters of new, emerging, or re-emerging human diseases are caused by pathogens from animals. The dilution effect—considered to be one of the most... Read More

A viral grappling hook: Flu virus attacks like a pirate boarding party

Viruses are biological pirates, invading cells and hijacking their machinery to reproduce and infect again. Research at Harvard Medical School is shedding new light on the battle line where viral and cell membranes meet, and the key role of a protein grappling hook with which the influenza virus... Read More

Modified Cold Sore Virus Shrinks Melanoma Tumors, Amgen Says

A genetically modified version of herpes simplex virus type 1, the same virus that causes cold sores, shrank tumors of the deadly skin cancer melanoma in a clinical trial, according to Amgen, which is developing the experimental cancer treatment.

Patients in the trial were in the late stages ... Read More

Pictures Considered. The E. coli Chromosome Caught in the Act of Replicating

We continue our series of images that have made a difference in microbiology. This one, published by John Cairns in 1963 has earned a most deserved place in textbooks and reviews. It shows a radioautograph of an intact E. coli chromosome in the act of replicating. From this image, Cairns conclud... Read More

Scientists describe development of drug that could treat, prevent malaria and block mosquito transmission

Drug successfully tested in mice; may be major advance as malaria has developed resistance to existing treatments

Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and prevent... Read More

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