A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal tran... Read More
DURHAM, N.C. -- Many bugs that make us sick -- bacteria, viruses, fungi and parasites -- hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles while leaving the rest of the living cell intact. Read More
Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More
There is currently no approved specific treatment or vaccine for dengue fever, and an estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on October 22nd in PLOS Pathogens introduces a candidate target for a tra... Read More
A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More
DNase agar can be used to differentiate between potentially pathogenic S. aureus and other Staphlococcus by looking for the presense of the exoenzyeme DNase. After growth for 24-48 hrs 1N HCL is added to the agar plate. Addition of HCL precipitates DNA in the media causing cloudiness unless t... Read More
Casein Plates contain the major milk protein found in milk. Organisms were grown on Casien agar for 72 hours at 37o C to look for the presence of the exoenzyme proteases/caseases . (A): Pseudomonas aeruginosa, casein hydrolysis, as noted by a zone of clearing around the organism, as well as a ... Read More
Enterococcus faecalis grown on blood agar for 48 hrs at 37 degree's C. Small, pin point, circular colonies can be seen with gamma hemolysis (no hemolysis of the blood agar). Colonies were white with a glossy translucent appearance. Read More
Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid®). Read More
Hi, I am doing a research in Cryptosporidium parvum and Cyclospora cayetanensis infection among School children of kathmandu at Public health research laboratory, the Institute of Medicne, kathmandu.
This is a Modified ZN stained image of Cyclospora cayetanensis isolated form a 5 year School... Read More
An international team of researchers has developed the largest genomic data set in the world on Lassa virus (LASV). The new genomic catalog contains nearly 200 viral genomes collected from patient samples in Sierra Leone and Nigeria, as well as field samples from the major animal reservoir, or h... Read More
This study done at department of Clinical Microbiology, TU Teaching Hospital , Kathamandu, Nepal.
Clinical specimen: Sputum
Media: Muller Hinton Agar
Incubation condition: at 37'c for 24hrs.
Isolate: Pseudomonas aerugionsa
Pic: Symbol of ASM.
Pseudomonas aeruginosa is a Gram-negative rod... Read More
Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More
For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More
Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More
Activated sludge. Note the bacterial rods and filament within the floc. (5000X) Read More
Four intracellular Toxoplasma gondii parasites are shown undergoing cellular division by an internal budding process known as endodyogeny. Staining with a T. gondii surface antigen provided heart-shaped images (shot on Valentine’s Day). The definitive host of these parasites is the cat, but they... Read More