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Beaded bacteriophage

This sculpture made of purple and clear glass beads depicts bacteriophage Phi174, a virus that infects bacteria. It rests on a surface that portrays an adaptive landscape, a conceptual visualization. The ridges represent the gene combinations associated with the greatest fitness levels of the vi... Read More

Dicty fruit

Dictyostelium discoideum is a soil-living amoeba. A group of 100,000 form a mound as big as a grain of sand.

The hereditary information is carried on six chromosomes with sizes ranging from 4 to 7 Mb resulting in a total of about 34 Mb of DNA, a multicopy 90 kb extrachromosomal element that h... Read More

Supernova bacteria

Bacteria engineered to act as genetic clocks flash in synchrony. Here, a "supernova" burst in a colony of coupled genetic clocks just after reaching critical cell density. Superimposed: A diagram from the notebook of Christiaan Huygens, who first characterized synchronized oscillators in the 17t... Read More

Arabidopsis leaf injected with a pathogen

This is a magnified view of an Arabidopsis thaliana leaf eight days after being infected with the pathogen Hyaloperonospora arabidopsidis, which is closely related to crop pathogens that cause 'downy mildew' diseases. It is also more distantly related to the agent that caused the Irish potato fa... Read More

Bacteriophage P22

Cross-section through the center of a three-dimensional (3D) reconstruction of P22 phage, which is a virus that infects Salmonella bacteria. P22 contains many copies each of nine different viral proteins and a single copy of a double-stranded DNA genome (shown in green). The centrally located po... Read More

Neisseria gonorrhoeae

This photomicrograph is showing Neisseria gonorrhoeae in a cervical smear using the Gram-stain technique. Thanks to the CDC's PHIL for the image. Read More

Mumps virus protein

This confocal micrograph shows the mumps virus protein (turquoise) in the endoplasmic reticulum of a cultured cell. This is a region of the cell that processes proteins. This particular protein is possibly involved in determining how effectively the virus can infect people. By looking at how it ... Read More

Whole genome analysis of Chlamydia trachomatis highlights risks with current method of tracking

In a study released today in Nature Genetics, researchers have found that Chlamydia has evolved more actively than was previously thought. Using whole genome sequencing the researchers show that the exchange of DNA between different strains of Chlamydia to form new strains is much more common th... Read More

Colorful cells

Actin (purple), microtubules (yellow), and nuclei (green) are labeled in these cells by immunofluorescence. This image won first place in the Nikon 2003 Small World photo competition.

Torsten Wittmann, Scripps Research Institute Read More

ARTS triggers apoptosis

Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue.

Sarit Larisch and Hermann Steller, Rockefeller University Read More

Cultured cells

This image of laboratory-grown cells was taken with the help of a scanning electron microscope, which yields detailed images of cell surfaces.

Tina Carvalho, University of Hawaii at Manoa. - NIGMS Image Gallery Read More

Parasitic Fungus Phragmidium tuberculatum on a rose leaf

Colorized scanning electron micrograph of rust on a rose leaf. Rose rust is a disease specific to roses and is caused by the parasitic fungus Phragmidium tuberculatum and some other closely related species. This disease occurs during spring and persists until the leaves fall. This images shows r... Read More

Escherichia coli - tight junction disassembly

This pair of confocal micrographs demonstrates how a disease-causing strain of E. coli bacteria brings about diarrhoea by breaking down the waterproof barriers between the cells. The bacteria are seen as small red dots attached to the surface of intestinal cells making tiny pedestals out of one ... Read More

Photos from the ASMBiodefense 2012 H5N1 Research Discussion

Moderated by the Chair of the National Science Advisory Board for Biosecurity (NSABB), Paul Keim, Ph.D., this session at the ASM Biodefense and Emerging Diseases Research Meeting included discussions of the NSABB’s recommendations for the publication of the controversial H5N1 research.

Presen... Read More

Cellular Aging

A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Normally, this protein is kept out of the nucleus with the help of gatekeepers known as nuclear pore complexes. But NIGMS-funded researchers found that wear and tear to long-lived compo... Read More

Finding One Bug

A new, nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Researchers attached nanoparticles, each packed with thousands of dye molecules, to an antibody that recognizes the microbe E. coli O157:H7. When the nanoball-antibody combo comes into contact with... Read More

A confocal micrograph of an intestinal biopsy from a child infected with shiga toxin-producing E. coli.

Shiga toxin is an extremely potent toxin that is produced when the bacterium contains a bacteriophage carrying the toxin gene. It is closely linked with Haemolytic Uraemic Syndrome and acute renal failure in children. After ingestion via contaminated food or water the E. coli bacteria colonize t... Read More

Portrait: Richard Lenski

Richard Lenski, Hannah Distinguished Professor, Michigan State University, at the American Association for the Advancement of Science meeting in Vancouver, British Columbia. Read More

Worm sperm motility

Two worm sperm shimmy across a microscope slide. Unlike most cells that rely on motor proteins to propel themselves forward, worm sperm use tiny fibers at their front ends. Putting the fibers together and taking them apart sets the cells in motion. In a new advance, researchers disassembled the ... Read More

Petri dish art

This tropical scene, reminiscent of a postcard from Key West, is actually a petri dish containing an artistic arrangement of genetically engineered bacteria. The image showcases eight of the fluorescent proteins created in the laboratory of Roger Y. Tsien, a cell biologist at the University of C... Read More

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