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Prion trials and tribulations: Finding the right tools and experimental models

Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies published on July 2nd in PLOS Pathogens report progress with novel tools an... Read More

New understanding of genetic susceptibility to infections by Candida and Mycobacterium

The discovery of bi-allelic mutations in RORC in patients with candidiasis and mycobacteriosis revealed the pivotal role of RORC in mucocutaneous immunity to Candida and in systemic immunity to Mycobacterium in humans. Read More

Stopping Candida in its tracks

Scientists are one step closer to understanding how a normally harmless fungus changes to become a deadly infectious agent. Read More

Scripps research-designed drug candidate significantly reduces HIV reactivation rate

HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS. Read More

Researchers develop world's most sensitive test to detect infectious disease, superbugs

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens. Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

Contaminant snowman

Some holiday fun from last winter composed of different collected plate contaminants. Based on colony morphology and wet mounts, these bacteria are likely to be: Staphylococcus sp. (white), Serratia marcescens (dark orange), and Micrococcus luteus (creamy yellow). The design was incubated for 5-... Read More

The next anti-tuberculosis drug may already be in your local pharmacy

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid®). Read More

It takes a village... to ward off dangerous infections? New microbiome research suggests so

ANN ARBOR, Mich. -- Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests. Read More

UGA researchers develop breakthrough tools in fight against cryptosporidium

Athens, Ga. - Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium, a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Their discoveries, published in the journal Nature, will ultimately help researchers in... Read More

Diarrhea in cats

Barbara Hinney and her colleagues from the Institute for Parasitology at the University of Veterinary Medicine, Vienna, screened 298 faecal samples taken from cats across Austria for single-cell intestinal parasites, so called enteric protozoa. The samples came from private households, catteries... Read More

Ebola

Ebola Virus
Colorized scanning electron micrograph of filamentous Ebola virus particles (blue) budding from a chronically infected VERO E6 cell (yellow-green).

Photo taken from NIAID flicker Read More

Unknown environmental Contaminant on blood agar plate streaked with S. pyogenes

A streak plate of Strep pyogenes on blood agar, stock culture used for class, was kept at room temp for 1 month. Before disposal a contaminant, presumably environmental, was seen on the plate. The pigment was opaque tan/yellow and with a mucoid surface. Lobate marigins with raised irregular-rh... Read More

Which is the morphology of this micro-organism?

Please help me! I am planning to identify this microorganism by API but I can not identify the shape (rod or cocci). This microorganism has positive oxidase. Its colony is red, irregular, flat.
Please teach me. Thanks so much! Nhu Thuy from Vietnam
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Shoe Swab

Unknown organism isolated from a swab taken off the bottom of a shoe. Students were asked to swab something in the classroom. One swab was done on the bottom of a shoe and incubated on a TSA plate for 48 hrs at 37 degree’s C. The organism was difficult to scrape so a small chunk of the organis... Read More

Bacillus/Diplobacillus

Simple stain done on an unknown bacteria, showing feathery rhizoid growth on TSA after a 48 hr incubation at 37 degree’s C, isolated from a floor swab. Single bacillus and diplobacillus can be seen though out. Read More

Beauty of Nocardia asteroides Colonies on Blood Agar

Nocardia asteroides isolation from blood specimen. On culture, chalky white colonies were seen on blood agar. Image courtesy MicrobeWorld user Kyriakos Zaragkoulias, Specialty Registrar (StR) in Medical Microbiology at General Hospital of Thessaloniki “G. Papanikolaou”, Greece.


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Swarming Motility of Pseudomonas aeruginosa

Strain: Pseudomonas aeruginosa PA14
Medium: M8 minimal medium agar plates
Incubation Conditions: 48 hours at 37°C
Pseudomonas aeruginosa is a gram-negative, rod-shaped and monoflagellated bacterium that has an incredible nutritional versatility. Swarming motility, a flagellum-dependent behavi... Read More

Yellow Unknown Yeast

Unknown yeast isolated on TSA from a swab taken from the bottom of a shoe incubated at 25 degrees C. Yellow, mucoid, round colonies were seen after 2 weeks. This isolate grew equally well at 37 degree C with a growth time of ~ 1 week. Read More

Orange Fungus image response

Image taken in Jamestown in March, similar to previous post. Several people in our dept have suggested chechen of the forest or SIlvershelf. Read More
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