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HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

Marburg virus virion

This colorized negative stained transmission electron micrograph (TEM), captured by F.A. Murphy in 1968, depicts a Marburg virus virion, which had been grown in an environment of tissue culture cells. Marburg hemorrhagic fever is a rare, severe type of hemorrhagic fever which affects both humans... Read More

Multidrug resistance Pseudomonas aeruginosa

Pseudomonas aeruginosa is one of the most notorious organisms that have brought the therapeutic dilemmas to clinicians as well as challenge to microbiologist throughout the world. It carries gene of intrinsic resistance (AmpC cephalosporinase, the OprD outer membrane porin, and the multidrug ef... Read More

Slime producing Staphylococcus epidermidis on Congo Red agar

Slime production by Staphylococcus epidermidis on Congo Red agar; demonstrated by black colored colonies. Slime production is one of the most important virulence factors produced by Coagulase negative Staphylococci.

The colonies of slime non-producing strains remain pink to red.
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Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

$7 million grant aids efforts to eliminate neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received a $7 million grant from the Bill & Melinda Gates Foundation aimed at eliminating river blindness and elephantiasis, two neglected tropical diseases that annually sicken millions. Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Bacteria biofilm

This confocal micrograph, taken as part of a synthetic biology project, shows Bacillus subtilis, a Gram-positive, rod-shaped bacterium that is commonly found in soil. Distinct lineages of bacteria expressing different fluorescent proteins were initially mixed randomly on a petri dish. As the bac... Read More

Herpes simplex, type 1

Herpes simplex, type 1. Isolate in human fetal diploid cell cultures, identified by direct FA staining Read More

Yellow Unknown Yeast

Unknown yeast isolated on TSA from a swab taken from the bottom of a shoe incubated at 25 degrees C. Yellow, mucoid, round colonies were seen after 2 weeks. This isolate grew equally well at 37 degree C with a growth time of ~ 1 week. Read More

Photo from Haiti: how to diagnose malaria and typhoid

These checklists, scrawled in handwriting on paper pasted to the hospital wall, are used by volunteer doctors and nurses to diagnose and treat patients who come in with symptoms of malaria and typhoid. Both are diseases that we rarely see in the US, but are strikingly common in Haiti. This also ... Read More

C. elegans sex-cell division

This montage of tiny, transparent C. elegans—or roundworms—may offer insight into understanding human infertility. Researchers used fluorescent dyes to label the worm cells and watch the process of sex-cell division, called meiosis, unfold as nuclei (blue) move through the tube-like gonads. Such... Read More

Pseudomonas aeruginosa with black extracellular pigment

Pseudomonas aeruginosa isolated from sputum into department of Microbiology - Riuniti Hospital Reggio Calabria .
This strain of Pseudomonas secretes brown/black extracellular pigment: pyomelanin.
Photo from D'Aleo Francesco archive. Read More

Streptococcus pneumoniae mucoid strain

Streptococcus pneumoniae cells are Gram-positive, lancet-shaped cocci. Usually, they are seen as pairs of cocci, but they may also occur singly and in short chains. In this photo a mucoid strain on blood agar showing alpha hemolysis (green zone surrounding colonies). Note the zone of inhibition ... Read More

Beauty of Nocardia asteroides Colonies on Blood Agar

Nocardia asteroides isolation from blood specimen. On culture, chalky white colonies were seen on blood agar. Image courtesy MicrobeWorld user Kyriakos Zaragkoulias, Specialty Registrar (StR) in Medical Microbiology at General Hospital of Thessaloniki “G. Papanikolaou”, Greece.


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Helicobacter fennelliae from blood culture

Helicobacter is a Gram-negative rod with a helical shape on gram stain. The most known strain is H. pylori, which causes ulcers and chronic gastritis and is said to affect up to 50% of the human population. This particular strain, Helicobacter fennelliae is most commonly found in the feces an... Read More

Brown hyphae of Exophiala jeanselmei

Brown hyphae of Exophiala jeanselmei. Hyphae in wall of 'cyst' Read More

HIV-infected H9 T Cell

Scanning electron micrograph of an HIV-infected H9 T cell. Credit: National Institutes of Health/Department of Health and Human Services (NIAID). Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

Great wave off Candida

Candida albicans is a yeast species that is part of the commensal microbiota of the body. Weakened or impaired immune system can lead to yeast infections mostly produced by Candida albicans, although other species like Candida parapsilosis, Candida glabrata and Candida tropicalis among others ar... Read More
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