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Spiral IV

Honorable Mention for Illustration: NSF 2004 International Science & Engineering Visulization Challenge

X-ray crystallographic data was used from real DNA molecules to paint a unique portrait of the double helix. The image omits the chemical bonds that crisscross the center of the molecule, s... Read More

Gram-positive cocci

Gram-positive cocci showing staphylococcus arrangement (970X). Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

Human Immunodeficiency Virus 3D

Illustration First Place Winner NSF International Science & Engineering Visualization Challenge

At first glance, it could pass for a piece of crochet, a fluffy gray and orange ball. But its real-world counterpart is far more destructive: It claims an estimated 2 million lives a year and has w... Read More

Neisseria gonorrhoeae diplococci

Type IV pilus filaments on Gram-negative bacterial pathogens control movement, attachment, immune escape, and natural transformation. Pili are attractive targets for vaccines and therapeutics because of the key role they play in bacterial virulence as well as their prominent cell surface exposur... Read More

H3N2 influenza virions

This transmission electron micrograph (TEM) depicts some of the ultrastructural details displayed by H3N2 influenza virions responsible for casing illness in Indiana and Pennsylvania in 2011.

The cases of human infection with swine-origin H3N2 influenza resulted from existing influenza virus... Read More

Stream Water Specimen

Under a relatively low magnification of 121X, this digitally-colorized scanning electron micrograph (SEM) of an untreated water specimen extracted from a wild stream mainly used to control flooding during inclement weather, revealed the presence of unidentified organisms, which included bacteria... Read More

Clostridium difficile

This is an image of Clostridium difficile colonies grown on cycloserine mannitol agar after 48 hours.

C. difficile, an anaerobic gram-positive rod, is the most frequently identified cause of Antibiotic-Associated Diarrhea (AAC). It accounts for approximately 15-25% of all episodes of AAC.

... Read More

Something in the water: Vibrio cholerae

Tiny rod-shaped bacteria called Vibrio cholerae cause cholera infections.

Credit: Tina Carvalho, University of Hawaii at Manoa

Related article: "The Quake that Brought Back Cholera" (http://publications.nigms.nih.gov/insidelifescience/cholera.html)
Allison MacLachlan
Posted August 10, 2... Read More

Viral desserts

At the Harvard Virology Program Retreat for 2011, the students ran a viral dessert contest. I posted some of the images at VirusTalk. Have a look at them – they are truly delicious. Read More

Bright red-orange photoluminescence observed from porous silicon nanoparticles with human HeLa cells

Bright red-orange photoluminescence observed from porous silicon nanoparticles with human HeLa cells, magnified 1000 times and viewed in the reflection from a silicon wafer. Prepared from high-purity silicon wafers, these nanoparticles provide a nontoxic and biodegradable alternative to conventi... Read More

Gram-positive cocci

Gram-positive cocci showing various morphological arrangements including diplococcus and tetrads. (approx. X970). Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

Dr. Robot (he kind of looks like one) is telling you . . .

. . . to do YOUR part to help stamp out what are now called STI's. Funny how as our knowledge of STI's and our ability to treat them has bloomed, our societal level of comfort with such PSAs seems to have withered. I used to see cleverly designed (and carefully/antiseptically couched) PSAs ab... Read More

Histoplasma capsulatum fungal macroconidium

At a magnification of 1125X, this photomicrograph revealed some of the ultrastructural morphology exhibited by a Histoplasma capsulatum fungal macroconidium. The reproductive spores produced by H. capsulatum can be either macroconidia or microconidia. It is the macroconidia that exhibits finger-... Read More

Gram-positive Listeria monocytogenes

Microscopic view of gram-positive Listeria monocytogenes (rods) (approx. original X 1,000). Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

B. subtilis spores

Simple crystal violet stained preparation mainly consisting of B. subtilis spores with a few scattered rods. Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

Red blood cell infected with malaria parasites

Colorized electron micrograph of red blood cell infected with malaria parasites (blue). The small bumps on the infected cell show how the parasite remodels its host cell. Uninfected cells (red) have smoother surfaces.
Credit: NIAID/RML

Related story: "Scientists Find Genetic Basis for Key Pa... Read More

Simple safranin stain of B. subtilis

Simple safranin stain of B. subtilis and central location of unstained spores. (Approx. original X 1000). Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

Staphylococcus aureus

Bacterial cells of the bacteria (Staphylococcus aureus) which is one of the causal agents of mastitis in dairy cows. Its large capsule protects the organism from attack by the cow’s immunological defenses. Magnified 50,000X. Freeze Drying Replication.

Credit: Beltsville Agricultural Research ... Read More

1918 influenza virions

This negative stained transmission electron micrograph (TEM) shows recreated 1918 influenza virions that were collected from supernatants of 1918-infected Madin-Darby Canine Kidney (MDCK) cells cultures 18 hours after infection.

To separate these virions, the MDCK cells are spun down (centrif... Read More

Plasmodium gallinaceum

This is a scanning electron micrograph of Plasmodium gallinaceum, which causes malaria in poultry, invading the midgut of the Aedes aegypti mosquito.
Credit: NIAID

"Fighting Drug-Resistant Malaria"
Rick Fairhurst and Others at NIAID Go Global
By Kristofor Langlais, NICHD, for the NIH Catal... Read More
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