MicrobeWorld App


Microbes After Hours


Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email


Featured Image

Featured Video

Ebola Outbreak 2014 2015 by Dr. Fauci


ASM House 200X200

Microbiology’s 50 Most Significant Events 1875–Present

Browse specific time periods.

1890 Emil von Behring and Shibasaburo Kitasato

890horseEmil von Behring and Shibasaburo Kitasato working together in Berlin in 1890 announce the discovery of diphtheria antitoxin serum, the first rational approach to therapy of infectious diseases. They inject a sublethal dose of diphtheria filtrate into animals and produce a serum that is specifically capable of neutralizing the toxin. They then inject the antitoxin serum into an uninfected animal to prevent a subsequent infection. Behring was awarded the Nobel Prize in Medicine or Physiology in 1901.

More Information:

Behring, E. 1890. Untersuchungen ueber das Zustandekommen der Diphtherie-Immunitat bei Thieren. Dt. Med. Wochenschr. 16: 1145-1148. In Milestones in Microbiology: 1556 to 1940, translated and edited by Thomas D. Brock, ASM Press. 1998, p141 [pdf]

Behring, E. and Kitasato, S. 1890. Ueber das Zustandekommen der Diphtherie-Immunitat und der Tetanus-Immunitat bei thieren. Deutsche medizinsche Wochenschrift 16:1113-1114 In Milestones in Microbiology: 1556 to 1940, translated and edited by Thomas D. Brock, ASM Press. 1998, p138 [pdf]

1890 Sergei Winogradsky

890soilSergei Winogradsky succeeds in isolating nitrifying bacteria from soil. During the period 1890-1891, Winogradsky performs the definitive work on the organisms responsible for the process of nitrification in nature.

More Information:

Winogradsky, S. 1890. Recherches sur les Organismes de la Nitrification.
Computer Rendu Vol 110: 1013-1016 In Milestones in Microbiology: 1556 to 1940, translated and edited by Thomas D. Brock, ASM Press. 1998, p231 [pdf]

1891 Paul Ehrlich

891erhlichPaul Ehrlich proposes that antibodies are responsible for immunity. He shows that antibodies form against the plant toxins ricin and abrin. With Metchnikoff, Ehrlich is jointly awarded the Nobel Prize in Medicine or Physiology in 1908.

1892 Dmitri Ivanowski

892tmvDmitri Ivanowski publishes the first evidence of the filterability of a pathogenic agent, the virus of tobacco mosaic disease, launching the field of virology. He passes the agent through candle filters that retain bacteria, but he isn't sure that the agent is a unique organism.

More Information:

When Did Virology Start, ASM News 62, 1996. p.142 [pdf]

Tobacco Mosaic Virus and Its Contributions to Virology, ASM News 65, 1999.p.675

1893 Theobald Smith and F.L. Kilbourne

893tickTheobald Smith and F.L. Kilbourne establish that ticks carry Babesia microti, which causes babesiosis in animals and humans. This is the first account of a zoonotic disease and also the foundation of all later work on the animal host and the arthropod vector.

1899 Martinus Beijerinck

Martinus Beijerinck recognizes "soluble" living microbes, a term he applies to the discovery of tobacco mosaic virus. He demonstrates that juice pressed from tobacco leaves that had been filtered free of bacteria retains the ability to cause disease in plants even after repeated dilutions. He calls the disease agent "contagium vivum fluidium" or contagious living fluid.

More Information:

Martinus Beijerinck (1851-1931), ASM News 62, 1996. p.539 [pdf]

Beijerinck, M. 1899. Ueber ein Contagium vivum fluidum als Ursache der Fleckenkrankheit der Tabaksblatter. Centralblatt fur bacteriologie und Parasirenkunde, Part II, 5: 27-33. In Milestones in Microbiology: 1556 to 1940, translated and edited by Thomas D. Brock, ASM Press. 1998, p153 [pdf]

No much more waiting around in line, viagra without perscription There are many other contributory elements to low-libido and failure plus they when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 pfizer viagra free samples This changed mindset of individuals regarding the cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that order viagra online Erection dysfunction is not just a disorder that causes problems that are buy female viagra online The dietary Content of Acai has amazed several of the whole buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a mucous-membrane distinguished. cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use