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Altering Gut Microbes Protects Against Disease, Supporting The 'Hygiene Hypothesis'

Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the journal Science. The study may also have uncovered reasons why females are at greater risk of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and lupus compared to males.

Researchers from The Hospital for Sick Children (SickKids) found that when female mice at high risk of autoimmune (type 1) diabetes were exposed to normal gut bacteria from adult male mice, they were strongly protected against the disease.

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