Celiac disease, an autoimmune disorder, is notoriously difficult to diagnose, particularly in its early stages. Now, researchers have developed a strategy to capture novel celiac disease antibodies. The technique successfully differentiated between sick and healthy people (Anal. Chem., DOI: 10.1021/ac303201d).
When patients with celiac disease eat wheat or other grains, their misfiring immune systems attack a grain protein called gluten sitting in their intestines, damaging nearby tissue. Immune system proteins called antibodies bind to intestinal tissues, marking them for destruction.
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