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Imaging combo spots infection in 3D

Scientists have combined MRI and imaging mass spectrometry to visualize the body’s inflammatory response to a bacterial infection in 3D. The techniques, described in Cell Host & Microbe, offer opportunities for discovering proteins not previously implicated in the inflammatory response.

Eric Skaar, chair in pathology at Vanderbilt University and his team were interested in imaging infection in three dimensions—in the whole animal—while also being able to identify the proteins that are produced at sites of infection.

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