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First genome-wide assessment of secretion in human cells

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An international collaboration between scientists in University College Dublin and the European Molecular Biology Laboratory (EMBL) has revealed for the first time that 15% of the proteins encoded by the human genome contribute to the process of secretion in cells. This finding has been made possible through the assessment of more than 8 million individual cells.

“This study is the first genome-wide assessment of the secretory process in a human cell system”, explains Professor Jeremy Simpson, UCD School of Biology & Environmental Science and UCD Conway Institute, co-author of the research paper published online today in Nature Cell Biology.

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