Previous exposure to certain antibiotics could boost the risk of infection with drug-resistant strains of a severe fungal infection. Researchers report their findings in the May 2012 issue of the journal Antimicrobial Agents and Chemotherapy.
Candida species are frequent causes of hospital acquired infection. Patients at greatest risk are those with “prolonged hospitalization, abdominal surgery, antibiotic treatment, neutropenia, and central venous catheterization,” the researchers write. Candidemia leads to high rates of “attributable” mortality, longer hospitalizations, and “excessive costs.”
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