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New Approach to 'Spell Checking' Gene Sequences

A PhD student from CSIRO and the University of Queensland has found a better way to 'spell check' gene sequences and help biologists better understand the natural world.

The student, Lauren Bragg, has contributed to the May issue of the journal Nature Methods highlighting her new approach and its software implementation called Acacia.

Acacia analyses the output of next-generation gene sequencing instruments which read the four-letter alphabet of As, Cs, Ts and Gs -- the 'bases' that code for DNA and spell out the genes of different living organisms. Acacia specifically applies to important parts of microbe genes called amplicons.

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