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Antimicrobial Resistance for Common Urinary Tract Infection Drug Increases Five Fold Since 2000

In a surveillance study of over 12 million bacteria, investigators at The George Washington University and Providence Hospital found E. coli antimicrobial resistance to ciprofloxacin, the most commonly prescribed antimicrobial for urinary tract infections in the U.S., increased over five-fold from 2000 to 2010. In addition, nearly one in four isolates in 2010 were resistant to trimethoprim-sulfamethoxazole (Bactrim®), the second most commonly prescribed drug for this infection.

This research was published in the April edition of the journal, Antimicrobial Agents and Chemotherapy.

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