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ARTS triggers apoptosis

ARTS_triggers_apoptosis.JPG
Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue.

Sarit Larisch and Hermann Steller, Rockefeller University
 
 

Comments (1)

  1. Not enough info for me. Here's more: "ARTS is an unusual septin-like mitochondrial protein that was originally shown to mediate TGF-beta-induced apoptosis." - The mitochondrial ARTS protein promotes apoptosis through targeting XIAP http://www.ncbi.nlm.nih.gov/pmc/articles/PMC391065/?tool=pubmed

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