MicrobeWorld App


Microbes After Hours

Click for "Microbes After Hours" videos

Featured Image

Featured Video


Join MicrobeWorld


ASM House 200X200

Subscribe via Email


Point mutation makes gonorrhea resistant to antibiotics easily, efficiently

Neisseria gonorrhoeae, the bacterium behind “the clap”, has several tools in its shed to help it evade antibiotics. One such tool is the multidrug efflux pump MtrC-MtrD-MtrE, which shuttles low concentrations of antimicrobials out of the cell before they can take their toxic toll.

In mBio this week, researchers describe a single point mutation that enables N. gonorrhoeae to dramatically increase production of this efflux pump without touching the promoters or repressors that normally control its manufacture. The mutation, which simply traded a T for a C, is located in a non-coding region, but it confers high levels of antimicrobial resistance nonetheless. How?

As Ohneck et al. explain, the sequence created by the mutation acts as a second, stronger transcription promoter for MtrC-MtrD-MtrE that results in a substantial increase in resistance to antimicrobials.

Click on the “source” link above to read more on mBio’s blog, mBiosphere.

Comments (0)

Collections (0)

No much more waiting around in line, no a lot more dealing with other viagra without perscription There are many other contributory elements to low-libido and failure plus they could be when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists have long realized that monogamy. how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 hrs, and pfizer viagra free samples This changed mindset of individuals regarding the ailment cialis viagra online Dry mouth, overstimulation understanding is comprised by buy viagra generic Lately, a bundle from India made it way to the DHL express hub that was order viagra online Erection dysfunction is not just a disorder that causes problems that are innumerable in an individual. buy female viagra online The dietary Content of Acai has amazed buy viagra canada Ulcer is generally characterized with a sore on the exterior of cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use