Many medical devices, ranging from artificial hip joints to dentures and catheters, can come with unwelcome guests – complex communities of microbial pathogens called biofilms that are resistant to the human immune system and antibiotics, thus proving a serious threat to human health. However, researchers may have a new way of looking at biofilms, thanks to a study conducted by University of Iowa biologist David Soll and his colleagues published in the Aug 2 issue of the online, open access journal PLoS Biology.
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"Alternative Mating Type Configurations (a/α versus a/a or α/α) of Candida albicans Result in Alternative Biofilms Regulated by Different Pathways" (http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001117)