MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

WaterSupplyYouTubeFrame

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Ebola Virus explained

Supporters

ASM House 200X200

Warning: imagecreatefromstring(): Data is not in a recognized format in /var/www/plugins/content/jlembed/jlembed.php on line 253 Warning: imagesx(): supplied argument is not a valid Image resource in /var/www/plugins/content/jlembed/jlembed.php on line 254 Warning: imagedestroy(): supplied argument is not a valid Image resource in /var/www/plugins/content/jlembed/jlembed.php on line 255

Engineering Excitable Cells for Studies of Bioelectricity and Cell Therapy

By altering the genetic makeup of normally "unexcitable" cells, Duke University bioengineers have turned them into cells capable of generating and passing electrical current.

This proof-of-concept advance could have broad implications in treating diseases of the nervous system or the heart, since these tissues rely on cells with the ability to communicate with adjacent cells in order to function properly. This communication is achieved through the passage of electrical impulses, known as action potentials, from cell to cell.

The researchers achieved this transformation by introducing genes into the cells that result in the formation of ion channels which are openings, or gates, on the surface of cells. Ion channels allow the flow of electrically charged molecules, or ions, to exit or enter the cell thus enabling the transfer of electric current from one cell to its neighbor.

Click "source" for entire article.

"Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies." (http://www.nature.com/ncomms/journal/v2/n5/full/ncomms1302.html)
 
 

Comments (0)

Collections (0)

 

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use