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Juvenile Diarrhea Virus Analyzed Down to the Atomic Level

Rice University scientists have defined the structure -- down to the atomic level -- of a virus that causes juvenile diarrhea. The research may help direct efforts to develop medications that block the virus before it becomes infectious.

The new paper by Professor Yizhi Jane Tao, postdoctoral researcher Jinhui Dong and their colleagues was published in the Proceedings of the National Academy of Sciences.

Tao's Rice lab specializes in gleaning fine details of viral structures through X-ray crystallography and computer analysis of the complex molecules, ultimately pinpointing the location of every atom. That helps researchers see microscopic features on a virus, like the spot that allows it to bind to a cell or sites that are recognized by neutralization antibodies.

Click "source" for entire article.

"Crystal structure of the human astrovirus capsid spike"
(http://www.pnas.org/content/early/2011/07/12/1104834108.abstract?sid=26e1d8e2-520b-4c1c-a883-62002444f2df)
 
 

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