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PH Values Control Formic Acid Metabolism In Bacterium

Formate, the salt of formic acid, is an important product of metabolism in bacteria and in contrast to human metabolism a preliminary stage of the gas carbon dioxide, which is released in the combustion of sugar. Enterobacteriaceae, a large family of bacteria including the intestinal bacterium Escherichia coli as well as pathogens like Vibrio cholerae and Salmonella typhimurium, possess the formate channel FocA, a specialized transport protein that transports the negatively charged ion of the formic acid over the cell membrane of the bacteria.

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