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New Strain of Listeria Can Carry Medicines And Vaccines

Scientists have used genetic engineering to tame one of the most deadly food poisoning microbes and turn it into a potential new way of giving patients medicine and vaccines in pills rather than injections. The study is in the current issue of ACS’ Molecular Pharmaceutics, a bi-monthly journal.

The scientists describe development of a new strain of Listeria monocytogenes, bacteria that normally cause food poisoning, but which have been genetically engineered to be harmless. Instead of causing disease, the new microbes can be loaded with medicine or vaccine, and deliver that beneficial cargo by “infecting” cells. After entering cells, the bacteria burst and die, leading to Pouton’s term “suicidal strain” for the microbes.

Via RedOrbit.com
 
 

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