After the eradication of smallpox in 1980, the World Health Organization called for destruction of known remaining stocks of the virus. The United States and Russia, which hold the known stocks of smallpox virus, have not destroyed their stocks. During TWiV #124, I was surprised to learn that the remaining stocks of smallpox are not just a few tubes of virus, but a substantial strain collection. With this information in mind, please take the poll below and register your position on the fate of smallpox virus.