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A guest post on Small Things Considered by S. Marvin Friedman, Professor Emeritus, Department of Biological Sciences, Hunter College of CUNY, New York City, reviews the various mechanisms thermophiles and hyperthermophiles may use to proliferate at extreme temperatures. Friedman wonders whether the basic questions regarding extreme thermal stability of proteins requires a "a different kind of biochemistry" explanation or if it's just that we don't have enough data to support a "regular" biochemistry answer yet.
 
 

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