MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

MWbannerEbola

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Oldest-life-on-earth

Supporters

ASM House 200X200

Staph’s Trail Points to Human Susceptibilities

Scientists have finally found an answer to one of the great mysteries about the most deadly bacteria, Staphylococcus aureus — why it attacks primarily humans and not animals. And they now have an idea of why some humans are particularly susceptible to these bacteria that kill 100,000 Americans a year, far more than any other microbe.

In a study released on Wednesday, researchers at Vanderbilt University report that staph evolved to zero in on particular regions of human hemoglobin so it could burst the cagelike molecule and feed on the iron inside. People who are resistant to staph, they suspect, might have slight genetic variations that tweak the hemoglobin regions the bacteria seek, making them impervious to the attack.

The work is part of a more general look at genes and disease. With new tools to look in detail at slight genetic variations, researchers are asking why some people get some diseases and others do not and why some die from diseases that others almost shrug off. With staph, for instance, 30 percent of the population harbors the bacteria in their noses, with no signs of infection.

Staph experts say the discovery, published in the Dec. 16 issue of Cell Host & Microbe, answers a lot of questions about the bacteria and shows them new directions for research.

“It’s terrific work,” said Frank DeLeo, acting chief of human bacterial pathogenesis at the National Institute of Allergy and Infectious Diseases. “It really is moving the field forward.”

The work began in 2002 when Eric P. Skaar was a postdoctoral fellow and fascinated by staph.

“Staph is the worst infectious threat to public health,” he said. “It is the No. 1 cause of heart infections and skin infections, the No. 1 cause of soft tissue infections. It is a big cause of pneumonia. It is the No. 1 hospital acquired infection.”
 
 

Comments (0)

Collections (0)

 
No much more waiting around in line, viagra without perscription There are many other contributory elements to low-libido and failure plus they when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 pfizer viagra free samples This changed mindset of individuals regarding the cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that order viagra online Erection dysfunction is not just a disorder that causes problems that are buy female viagra online The dietary Content of Acai has amazed several of the whole buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a mucous-membrane distinguished. cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use