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How Smallpox May Derail Human Immune System

University of Florida researchers have learned more about how smallpox conducts its deadly business — discoveries that may reveal as much about the human immune system as they do about one of the world's most feared pathogens.

In findings to be published this week in the online early edition of the Proceedings of the National Academy of Sciences, scientists describe how they looked at all of the proteins produced by the smallpox virus in concert with human proteins, and discovered one particular interaction that disables one of the body's first responders to injury — inflammation.

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