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Discovery of Controlled Swarm in Bacteria: Could Help Design New Strategies to Increase Sensitivity to Antibiotics

A study led by researchers from Universitat Autònoma de Barcelona (UAB) describes one of the mechanisms in which pathogenic bacteria populations control the way they spread over the surface of the organs they infect and stop when they detect the presence of an antibiotic, only to resume again when the effect wears off. The star of this process is the RecA protein, which significantly increases its concentration at the start of the bacteria DNA repair mechanism induced by antibiotics.

The research was carried out with Salmonella enterica, member of a bacteria group found in several pathogenic species responsible for diseases in the digestive and respiratory system, such as septicaemia and systemic infections.

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