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New Understanding of Dengue Fever Could Help With Vaccine

Some of the human immune system's defences against the virus that causes dengue fever actually help the virus to infect more cells, according to new research published May 6 in the journal Science.

The researchers behind this study have identified a set of antibodies, produced by the human immune system to fight off the dengue virus, that they believe scientists should avoid including in any new vaccine to prevent dengue fever.

The new research shows that these precursor membrane protein (prM) antibodies do not do a very effective job of neutralising the virus. Moreover, these antibodies actually help the virus to infect more cells.

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