MicrobeWorld App


Microbes After Hours

Click for "Microbes After Hours" videos

Featured Image

Featured Video


Join MicrobeWorld


ASM House 200X200

Subscribe via Email


Warning: imagecreatefromstring(): Data is not in a recognized format in /var/www/plugins/content/jlembed/jlembed.php on line 253 Warning: imagesx(): supplied argument is not a valid Image resource in /var/www/plugins/content/jlembed/jlembed.php on line 254 Warning: imagedestroy(): supplied argument is not a valid Image resource in /var/www/plugins/content/jlembed/jlembed.php on line 255

Sheep Virus Life Cycle That Causes Malignant Catarrhal Fever Explained

The mysterious life cycle of a sheep virus that causes malignant catarrhal fever (MCF) has been discovered by Agricultural Research Service (ARS) scientists and their university collaborators -- the first step in developing a vaccine against the disease.

Microbiologist Hong Li and veterinary medical officer Naomi Taus at the ARS Animal Diseases Research Unit in Pullman, Wash., collaborated on the research with Lindsay Oaks at Washington State University and Donal O'Toole at the University of Wyoming.

MCF, a viral infection that is a leading cause of disease in American bison, is usually transmitted from sheep to bison and cattle. Vaccine development has been stymied because the virus won't grow in cell culture.

The ARS scientists and their university colleagues have shown that the virus undergoes several changes inside the animal's body, targeting specific cell types at different stages of its own life cycle. This process is called "cell tropism switching."

The viral replication in sheep can be divided into three stages: entry, maintenance, and shedding. The virus enters the sheep through its nasal passages and reaches the lungs, where it replicates. Replication in the sheep lung is required for the virus to change its cell tropism for the next stage: the infection of lymphocytes, a type of immune cell.

Comments (0)

Collections (0)

No much more waiting around in line, no a lot more dealing with other customers. Purchasing requires. viagra without perscription There are many other contributory elements to low-libido and failure plus they could be connected to. when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists have long realized that monogamy. how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 hrs, and then very P-Force pfizer viagra free samples This changed mindset of individuals regarding the ailment is however not a surety cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that was shops. Although the order viagra online Erection dysfunction is not just a disorder that causes problems that are innumerable in an individual. buy female viagra online The dietary Content of Acai has amazed several buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use