MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

MWbannerEbola

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Oldest-life-on-earth

Supporters

ASM House 200X200

Resistance to swine flu antiviral drugs can develop faster than expected, research finds

Image
The pandemic H1N1 influenza virus can develop resistance to the commonly used antiviral drugs much faster than expected, federal researchers said Friday. Previous research had suggested that it would take 24 days or longer for resistance to the drugs to develop in a patient, but a new study reported in the journal Clinical Infectious Diseases found that resistance could appear in as little as nine days. The study also found that one patient developed resistance to the experimental intravenous drug peramavir, the first time clinically significant resistance to that drug has been observed.

Dr. Matthew J. Memoli and Dr. Jeffrey K. Taubenberger of the National Institute of Allergy and Infectious Diseases reported on two immunocompromised patients who developed persistent swine flu infections. Both patients had undergone blood stem cell transplants several years earlier. The resistant form of the virus appeared in one patient after 14 days and in the second after nine days.

Both patients received oseltamivir (Tamiflu) for extended periods, but continued to shed virus -- a sign that the virus had developed resistance to the drug. When one patient's condition worsened despite 24 days of treatment, he was given peramivir for 10 days. The patient continued shedding virus, indicating that the virus had become resistant to that drug too. Laboratory tests confirmed the resistance. The patient was then given the only remaining antiviral, zanamivir (Relenza) for 10 days and fully recovered. Zanamivir must be inhaled, however, and many seriously ill patients are not able to take it for that reason.
 
 

Comments (0)

Collections (0)

 
No much more waiting around in line, viagra without perscription There are many other contributory elements to low-libido and failure plus they when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 pfizer viagra free samples This changed mindset of individuals regarding the cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that order viagra online Erection dysfunction is not just a disorder that causes problems that are buy female viagra online The dietary Content of Acai has amazed several of the whole buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a mucous-membrane distinguished. cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use