MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

MWbannerEbola

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Oldest-life-on-earth

Supporters

ASM House 200X200

Soil switches on antibiotic genes in bacteria

Image
So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. The researchers used soil extracts to persuade a Clostridium species to produce a hitherto unknown antibiotic that is active against methicillin-resistant Staphylococcus aureus (MRSA).

Many antibiotics made by bacteria are produced through non-essential biosynthetic pathways - they are secondary metabolites. But getting anaerobic bacteria, like those from the Clostridium genus, to produce these compounds has, until now, proved difficult. Having delved into the recently published genome of C. cellulolyticum, however, Christian Hertweck at the Hans Knöll Institute in Jena was convinced it would be worth the trouble.

'We saw some typical genes that code for biosynthetic machineries such as those in antibiotic producers,' says Hertweck. 'We call these cryptic gene clusters, because it's absolutely not clear what they're good for.' Their plan was to wake up these sleeping genes by exposing the bacteria to different environmental conditions.
 
 

Comments (0)

Collections (0)

 
No much more waiting around in line, viagra without perscription There are many other contributory elements to low-libido and failure plus they when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 pfizer viagra free samples This changed mindset of individuals regarding the cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that order viagra online Erection dysfunction is not just a disorder that causes problems that are buy female viagra online The dietary Content of Acai has amazed several of the whole buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a mucous-membrane distinguished. cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use